Tag Archive: translational

Nov 13 2018

New Center for Computational and Genomic Medicine Harnesses Technology and Big Data for Discovery

The Human Genome Project’s successful completion 15 years ago gave us a new genomic lens to read our 20,000 or so protein-coding genes. Since then, a surge in next-generation sequencing technologies is generating new insights daily that sharpen our view of how the human genome works.

Yi Xing, PhD, was on the cusp of this revolution in medicine as he finished his PhD training in molecular biology and bioinformatics at University of California Los Angeles (UCLA). His research career began to rise during the incredible takeoff of big data science, and he became a prominent scientist in this cutting-edge field. The immense challenges of synthesizing diverse data sets from many sources come with vast opportunities to change pediatric medicine, which is why Dr. Xing is eager to assume his new role as the inaugural director of the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia.

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Apr 16 2018

Researchers Target Brain Circuity as Driver of Antidepressant Behavior

Neurobiology researchers at Children’s Hospital of Philadelphia are looking deep into the brain’s circuitry to search for new avenues for the treatment of major depressive disorder, the most common mental illness.

In 2016, 10.3 million adults had at least one major depressive episode with severe impairment, according to the National Institute of Mental Health. While care by a health professional and antidepressant medication may be effective for some people, current treatments have a high rate of relapse and side effects.

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