It was a pivotal moment that has turned into a new era for cancer immunotherapy. On April 17, 2012, Children’s Hospital of Philadelphia researchers for the first time treated a pediatric patient with a cellular therapy that used her own reprogrammed immune cells, called T cells, to attack her aggressive form of blood cancer.
Tag Archive: T cells
When you have a chronic allergic disorder, it’s easy to blame the trigger — an early pollen season or furry pet — but the real culprit is your own immune system. Designed to attack foreign substances such as bacteria and viruses, T cells are the immune system’s watchdog to recognize serious threats. But sometimes T cells can be too zealous and set in motion a signaling cascade that can cause allergic reactions to everyday things and even attack your body’s healthy cells by mistake.
Your immune system is designed to protect against foreign invaders such as infections, but you may not realize that it also destroys abnormal cells that your body produces.
Cookies for Kids’ Cancer, a nonprofit foundation dedicated to pediatric cancer research, uses the proceeds from its cookie sales and other fundraising events to provide grants to support the work of scientists at five of the nation’s leading pediatric cancer centers.
An innovative cell therapy for this stubborn form of leukemia continues to show highly promising results in children treated in a pilot clinical trial.
The Children’s Hospital of Philadelphia’s groundbreaking leukemia research was on display at the recent American Society of Hematology (ASH) Annual Meeting. Held in New Orleans, the ASH Annual Meeting brought together approximately 20,000 researchers, clinicians, and industry representatives, with data from more than 5,300 abstracts presented.
The Children’s Hospital of Philadelphia’s Stephan A. Grupp, MD, PhD, along with his young patient Emily Whitehead, were recently named 2013 WebMD Health Heroes.
The groundbreaking immune therapy work being done by The Children’s of Hospital of Philadelphia’s Stephen M. Grupp, MD, PhD, was recently highlighted on Australia’s 60 Minutes.
The innovative work being done by CHOP’s Stephen Grupp, MD, was recently featured on the CBS show The Doctors. Dr. Grupp, the Center for Childhood Cancer Research’s director of translational research, discussed his trial using immune therapy to treat an aggressive form of childhood leukemia, acute lymphoblastic leukemia (ALL).