Tag Archive: Perelman School of Medicine

Mar 21 2018

Lifespan Brain Institute Symposium Dig Into Roots of Mental Illness

Leaders of the Lifespan Brain Institute (LiBI) brought together experts in child and adult psychiatry, and basic and translational science, to delve into the origins of mental illness, during the Institute’s first symposium, “Pathological Antecedents to Neuropsychiatric Disorders.” Throughout the day, 200 attendees learned about how the typical trajectory of brain development and function is derailed in psychiatric disorders at various points throughout life — perhaps as early as in the womb.

LiBI is uniquely positioned as a broad collaboration between Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania that supports research across the fetal-adult continuum, which is a pillar of CHOP Research Institute’s strategic plan.

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Jan 11 2018

Is Autism Associated With Stronger or Weaker Brain Connections?

The Finding:

In a new study that sheds light on a longstanding paradox in autism research, investigators showed how children and teens with autism spectrum disorder (ASD) can have both stronger and weaker brain connections than their typically developing peers. Resting-state functional magnetic resonance imaging (fMRI) revealed that while individuals with ASD have weaker brain connections compared to their peers overall (a measure known as absolute connectivity), they simultaneously exhibited stronger connections within the brain networks implicated in attention and social cognition compared to their other networks (a measure known as relative connectivity). Additionally, the more these brain connections differed from typical development, the more severe the child’s ASD symptoms seemed to be.

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Dec 27 2017

Our Most Read Stories of 2017 Bring Back the Wonder of Childhood

It was a big year for children’s health: We celebrated the U.S. Food and Drug Administration’s approval of the world’s first chimeric antigen receptor (CAR)-T cell therapy this September, followed closely by approval of the very first gene therapy to treat inherited blindness this month — both of which have their roots at Children’s Hospital of Philadelphia and the University of Pennsylvania. But besides the big headline-making breakthroughs (brilliant as they are), we wanted to know what other stories captivated our readers in 2017.

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Dec 5 2017

Three Key Questions for Breaking Into Translational Research

Breakthroughs in basic science build the foundation for clinical research and our treatment of children’s health. Many basic scientists, however, find themselves wanting to play a more active role in connecting their lab discoveries from the bench to the bedside. The Office of Postdoctoral Affairs at Children’s Hospital of Philadelphia held a Q&A panel, “How to Break Into Translational Research As a Basic Scientist,” in October as part of their week-long, biannual Translational Research Workshop.

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Nov 17 2017

Artful Thinking, Teledermatology App, Genetic Mutations in Hearing Loss, Dr. Vinay Nadkarni

Art meets medicine and cell phones support skin diagnoses in this week’s roundup of research news at Children’s Hospital of Philadelphia, as our latest headlines show science can find the best partners in unlikely places. Along with a creative study on the power of art observation for ophthalmology led by Gil Binenbaum, MD, MSCE, pediatric eye surgeon at CHOP, we also cover updates from researchers developing a teledermatology app, learn about novel pathways in the gene mutations that cause hearing loss, and congratulate Vinay Nadkarni, MD, on his latest honor from the American Heart Association.

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Jul 28 2017

Psychology in Media Award, Targeted Cancer Drugs, Dermatology App, CHOP ROP Model, Beckwith-Wiedemann Conference

CHOP Research In the NewsRead on for more exciting headlines from this week, including highlights from our inaugural “Deciphering Beckwith-Wiedemann Syndrome” conference.

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Jun 30 2017

Measuring Flexible Thinking, Managing Concussions, Tech Addiction, 2017 Pew Scholar, U.S. News & World Report

CHOP Research In the NewsEvery good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.

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May 11 2017

How Can We Improve Nurse Response Times to Bedside Alarms?

When it comes to bedside alarms for conditions like low oxygen saturation, tachycardia, or cardiac arrhythmias, four main factors contribute to faster nurse response times.

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Mar 15 2017

CHOP Named the Nation’s Best Pediatrics Department for 2018

PediatricsFor the fifth year in a row, we are excited to announce that U.S. News & World Report’s annual survey has awarded our department of Pediatrics at Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania first place in pediatric medical education.

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