Tag Archive: Neuroblastoma

Mar 6 2019

Patricia Brophy Chair Holds ‘Immeasurable’ Meaning for Yael Mossé, MD

By Jillian Rose Lim

Yael Mossé, MD, remembers meeting Patricia “Pat” Brophy, beloved nurse practitioner at Children’s Hospital of Philadelphia, nearly 23 years ago. Dr. Mossé was completing her pediatric residency, while Brophy was already a seasoned nurse caring for the sickest of children with cancer. Intrigued by the prospect of specializing in neuroblastoma, a cancer of the nervous system, Dr. Mossé reached out to Brophy to learn more about the disease that left children with limited treatment options. What began as a mentorship soon blossomed into a friendship spanning two memorable decades.

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Feb 22 2019

In the News: Sleep Problems and Autism, Opioid Overprescription, Food Pharmacy, Gun Violence Prevention, Proof-of-Concept Award, and Lung Cells in Fetal Development

By Nancy McCann

We start this edition of In the News with a look at the prevalence of sleep problems in young children with autism spectrum disorder, a study on opioid prescriptions for kids with broken elbows, and Children’s Hospital of Philadelphia’s grand opening of the Healthy Weight Food Pharmacy and the research behind it.

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Dec 31 2018

Our Most Read Stories of 2018 Celebrate Diversity, Data, and Discovery

As the new year approaches, we look back with gratitude for yet another year packed with scientific breakthroughs in children’s health. Continuing a remarkable run for personalized gene therapies, 2018 marked the European Commission’s approval of two gene therapies pioneered at Children’s Hospital of Philadelphia and the University of Pennsylvania, as patients in the European Union (EU) may now be treated with chimeric antigen receptor (CAR)-T cell therapy for aggressive forms of leukemia, and the very first gene therapy developed for inherited blindness.

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Dec 28 2018

In the News: Study Tops Most-Read List, the Migratory T Cell Response, Mossé Named Endowed Chair, ‘Healthier Together’ Launches, Supporting Survivors

Leading the charge to develop new, targeted approaches to treat disease, Children’s Hospital of Philadelphia Research Institute investigators have uncovered more of the mechanistic underpinnings of the migratory T cell response, and CHOP announced the inaugural Patricia Brophy Endowed Chair in Neuroblastoma Research to advance innovation into less toxic treatment options for specific cancers. Out in the community, CHOP has teamed up with the Philadelphia Housing Development Corporation for the pilot program of its Healthier Together initiative, and researchers are learning how best to help survivors of violence after they are discharged from the hospital.

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Apr 20 2018

Emily Whitehead Anniversary, Buchanan Lectureship, Hyundai Young Investigators, Yi Xing, New York Auto Show

Cars, computational biology, and cancer advances are all featured in this week’s roundup of Children’s Hospital of Philadelphia research news, as our investigators received recognition at places as far as the New York International Auto Show, and as close as our hospital’s own Seacrest Studios. Read on to learn more about new awards from Hyundai’s nonprofit organization, Hope on Wheels, the Emily Whitehead Foundation’s generous gift to our Cancer Immunotherapy Frontier Program, and more!

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Mar 9 2018

Lung Stem Cells, 2021 Congress of the ISTH, Backseat Safety, Pan-Cancer Analysis, Gates Cambridge Scholarship

From the discovery of stem cells that multiply after a lung injury, to new data that advances how we think about (and treat) childhood cancer, our first roundup of March is packed with discovery. Read on to learn how our researchers stay at the forefront of pediatric science with a new study that expands what scientists know about the body’s extraordinary ability to regenerate, a pan-cancer project that distinguishes how cancer develops in children versus adults, and a handful of updates on what our investigators have in store for the near future.

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Feb 26 2018

John Maris, MD, Receives National Cancer Institute Outstanding Investigator Award

Long before he entered medical school, John M. Maris, MD, pediatric oncologist and the recent recipient of the National Cancer Institute’s Outstanding Investigator Award, became captivated by the mysteries of neuroblastoma. A cancer of the peripheral (not brain) nervous system, neuroblastoma accounts for 7 percent of all childhood cancers and 15 percent of all childhood cancer deaths.

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Oct 13 2017

Translational Research Workshop Bridges Gap Between Bench Research and Clinic

If you glance at a diagram of the continuum of translational research, the arrows point orderly to five phases — from basic research to improving population health. Rarely, however, is the business of discovery so neatly aligned. It takes unexpected twists and turns, as attendees at this week’s Children’s Hospital of Philadelphia Translational Research Workshop for Basic Scientists heard from experienced investigators who shared lessons that they’ve learned while pursuing their scientific endeavors.

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Oct 6 2017

Neuroblastoma Gene Variants, Center for GI Motility Expansion, Improving Autism Diagnosis, Fontan Procedure Follow-Ups

CHOP Research In the NewsThis week, new research findings at Children’s Hospital of Philadelphia are propelling the way we think about autism, single ventricle survivors, and neuroblastoma forward, as our investigators continued to push the boundaries of what we know.

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Sep 29 2017

Researchers Win Grants to Explore New Drug Targets for Childhood Cancers

National Childhood Cancer Awareness Month is coming to a close, but new research endeavors are continuing the momentum and driving toward better treatment options.

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