Tag Archive: Mitochondria

Sep 21 2018

In the News: Brain Cancer Gene Therapy, 2019 Eagles Autism Challenge, Mitochondrial DNA in Cardiomyopathy, Kids First DRC, Device Symposium

Fall weather and football season have returned to us here at Children’s Hospital of Philadelphia Research Institute, bringing with them a fresh batch of research headlines. In this edition of our biweekly news roundup, catch up on the latest announcements for the second annual Eagles Autism Challenge, learn about new insights into the role mitochondrial DNA plays in heart disease progression, and stay updated on how CHOP helps to drive medical innovation and entrepreneurship forward in the Philadelphia community and beyond.

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Dec 27 2017

Our Most Read Stories of 2017 Bring Back the Wonder of Childhood

It was a big year for children’s health: We celebrated the U.S. Food and Drug Administration’s approval of the world’s first chimeric antigen receptor (CAR)-T cell therapy this September, followed closely by approval of the very first gene therapy to treat inherited blindness this month — both of which have their roots at Children’s Hospital of Philadelphia and the University of Pennsylvania. But besides the big headline-making breakthroughs (brilliant as they are), we wanted to know what other stories captivated our readers in 2017.

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Oct 27 2017

Friedreich’s Ataxia Community Stays on Top of Science and Stays in Touch

Patients and families dealing with the rare, debilitating disease Friedreich’s Ataxia showed their true strength at the 10th Annual Friedreich’s Ataxia Symposium held in King of Prussia, Pa. The FA community is a steadfast supporter of research, and they have been gathering for a decade to spend a day with each other building friendships and learning the most up-to-date information on the therapeutic approaches and scientific studies being conducted in the field of FA.

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Sep 8 2017

CAR-T Cell Approval, Hope on Wheels, Task Force on Pregnant Women, Taking Flight for Autism, NFL Concussion Research, Doug Wallace

CHOP Research In the NewsSeptember marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research. Oncology investigators at CHOP also got a big boost in research funding from Hyundai’s nonprofit organization, Hope on Wheels. And that’s only the beginning: Since September marks the return of the football season, we’re thrilled to share the latest headlines on how the National Football League (NFL) is helping to drive concussion research.

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Aug 23 2017

Mitochondrial Gene Defects Associated With Autism Traced Back to Ancient Times

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.

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Jan 12 2017

Novel Imaging Tool Estimates Energy Production in Mitochondrial Diseases

mitochondrial diseaseFitness tools that monitor your daily use of energy, from counting steps to tracking sleep, have exploded in popularity. Researchers are developing better noninvasive, high-resolution methods to estimate how well the fundamental source of that energy — your mitochondria — are working, and they have recently had some important successes.

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Oct 21 2016

CHOP Research In the News: Cancer Moonshot Yields Data-Sharing Initiatives, Hemophilia Surprise, Mitochondrial Medal

CHOP Research In the NewsBuckle your seatbelts because this has been a busy week for research news at Children’s Hospital of Philadelphia.

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May 24 2016

Underpinnings of Neuropsychiatric Disease: A Behavioral Health Research Q&A

behavioral healthA self-proclaimed “geeky student” in high school, Stewart Anderson, MD, a research psychiatrist, always dreamed of being a scientist. He wandered through various fields — anthropology, archeology, geology, astronomy – before becoming fascinated with learning about the brain.

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Dec 17 2015

Mitochondria Affect How We Respond to Stressful Environments

mitochondriaNew research suggests that the tiny structures inside our cells that generate energy, called mitochondria, may play a role in our mind-body interactions and how we respond to stressful environments.

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Nov 4 2015

Tiny Mitochondria Play Outsized Role in Human Evolution and Disease

Cells under microscopeMitochondria are not only the power plants of our cells; these tiny structures also play a central role in our physiology. Furthermore, by enabling flexible physiological responses to new environments, mitochondria have helped humans and other mammals to adapt and evolve throughout the history of life on earth.

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