Tag Archive: microbiome

Jul 18 2018

CHOP’s Inflammatory Bowel Disease Symposium Attracts Leading Experts

With the rate of inflammatory bowel disease (IBD) continuing to rise, especially in the hard-the-treat population of young children, the timing couldn’t be better for the Children’s Hospital of Philadelphia’s “Personalized IBD and VEO-IBD: Genomics, Microbiome, Biologics, and Beyond” symposium.

This symposium was of particular interest because of the unique combination of the latest research developments with the most up to date advances in clinical care for very-early-onset inflammatory bowel disease (VEO-IBD) and pediatric IBD, said course Co-director Judith R. Kelsen, MD, director of CHOP’s Very Early Onset Inflammatory Bowel Disease Clinic.

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Jul 10 2018

Do Oral Antibiotics Play a Role in Kidney Stone Prevalence Increase in Youth?

The Findings: Children and adults treated with five classes of oral antibiotics have a significantly higher risk of developing kidney stones. The five classes include oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins. Patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones. For broad-spectrum penicillins, the increased risk was 27 percent higher. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics. The risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

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Jun 18 2018

BWF Awards Recognize Young Investigators, Innovative Research

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Mar 2 2018

Exploring the Wide World of the Microbiome

Studying the microbiome — the 40 trillion or so invisible microbes that call your body home — is like being an explorer of a secret world with its own language and lifeforms. Whether these microbes are sometimes friends or sometimes foe depends on subtle interactions with each other and the role of influential factors such as your genetics, environment, age, and diet.

The PennCHOP Microbiome Program awards annual pilot and feasibility grants to help faculty members of the University of Pennsylvania and Children’s Hospital of Philadelphia scientific communities navigate this uncharted territory. With the funding awarded in 2017, eight projects are underway, and CHOP clinician-scientists are leading two of them.

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Aug 9 2016

“We’re Just Laughing About Poop”: A Clinical Research Study Experience Q&A

Clinical Research StudyNot every child who comes to the hospital is sick. Some of the families who visit The Children’s Hospital of Philadelphia on a regular basis are voluntary participants in research studies. Clinical research studies are an essential component of pediatric research that can lead to novel discoveries and advancements for populations in need.

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Jul 5 2016

On Your Skin, In Your Gut, and All Around: A Microbiome Q&A

microbiomeMicrobes are on us and in us, and researchers are increasingly becoming aware that they are a vital part of us. Across The Children’s Hospital of Philadelphia and University of Pennsylvania a variety of research efforts are underway to understand these populations of bacteria, viruses, and other tiny life forms, known as the microbiome, and their impact on health.

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Feb 9 2016

CHOP Research Annual Report 2015: The Future Is Here — Don’t Miss It

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Scientific minds are imagining. Sophisticated machines are harnessing genetic data. An invisible universe of microbes is revealing new insights into disease. Discoveries are changing children’s worlds. Every second of every day is filled with wonder at The Children’s Hospital of Philadelphia Research Institute.

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Feb 2 2015

Research Collaborative Aims to Advance Understanding of Preterm Birth

preterm birthResearchers and physicians at The Children’s Hospital of Philadelphia are part of a transdisciplinary team that will apply sophisticated technology and methodology in molecular biology and genomics to help better understand the basis for preterm birth.

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Sep 29 2014

Antibiotic Use in Infancy May Play Role in Obesity

obesityDr. Bailey and colleagues observed an increased risk of obesity with greater antibiotic use, particularly for children with four or more exposures to broad-spectrum antibiotics in early childhood.

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Sep 22 2014

Healthy Weight Program Launches Study on Microbiome

microbiomeKnown as the microbiome, this complex collection’s potential role in early weight gain and obesity has become a fascinating area of scientific exploration.

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