Tag Archive: microbiome

Mar 1 2019

Uncovering the Unexpected: Q&A With Jean-Bernard Lubin, PhD, New Diversity Fellow

It’s been an exciting week on Cornerstone, as we’ve gotten to know the newest recipients of the Postdoctoral Fellowship for Academic Diversity and learn about the richness of experience they bring to our research community.

Closing our three-part Q&A series is Jean-Bernard Lubin, PhD, who discovered the perfect place to pursue his research interests in the microbiome and its effects throughout the lifespan. With the goal of directing the course of those effects with therapeutic interventions, Dr. Lubin brings his passion for bacterial genetics to CHOP.

Read the rest of this entry >>

Feb 27 2019

Stronger Communities Through Research: Q&A With Phylicia Fitzpatrick Fleming, PhD, New Diversity Fellow

As part of a three-part Q&A series on Cornerstone, we’re introducing new members of the Children’s Hospital of Philadelphia research community. The Postdoctoral Fellowship for Academic Diversity supports our belief that innovation is enhanced when a diverse group of researchers from a variety of backgrounds, disciplines, and perspectives contribute to solutions.  In this series, we’re learning more about our newest Diversity Fellows through their own voices, taking us on a journey from where their research paths began to their favorite pastimes.

Read the rest of this entry >>

Feb 25 2019

Merging Mechanics and Human Movement: Q&A With Ozell Sanders, PhD, New Diversity Fellow

Breakthroughs occur when great minds from a variety of backgrounds join together in the spirit of innovation. At Children’s Hospital of Philadelphia, we see diversity as a key driver of achievement and crucial when the accomplishments at stake have the potential to change, and even save, children’s lives. Among the ways CHOP demonstrates its commitment to diversity in research is the Postdoctoral Fellowship for Academic Diversity. Three new diversity fellows recently joined the CHOP research community, bringing the wealth of their unique education, training, and life experiences. In a three-part Q&A series, we’ll learn more about these scholars, their areas of expertise and interest, and even a little bit about how they spend their hard-earned downtime.

Read the rest of this entry >>

Nov 21 2018

In the Gut: Therapeutic Discovery in the Microbiome

 


The Fifth Annual Microbiome Symposium: Microbes, Metabolomics, and Modern Diseases highlighted the synergy of the Children’s Hospital of Philadelphia and University of Pennsylvania scientific community to produce incredibly novel and exciting research.

Hosted by the PennCHOP Microbiome Program, the Nov. 8 symposium brought experts from the fields of microbiology, immunology, gastroenterology, cell and molecular physiology, and pathology together with a common goal: to share developments from their labs with the end game of improving outcomes for individuals with chronic disease.

Larry Jameson, MD, PhD, executive vice president, University of Pennsylvania Hospital System and dean of the Perelman School of Medicine, welcomed attendees to the packed Gaulton Auditorium.

Read the rest of this entry >>

Jul 18 2018

CHOP’s Inflammatory Bowel Disease Symposium Attracts Leading Experts

With the rate of inflammatory bowel disease (IBD) continuing to rise, especially in the hard-the-treat population of young children, the timing couldn’t be better for the Children’s Hospital of Philadelphia’s “Personalized IBD and VEO-IBD: Genomics, Microbiome, Biologics, and Beyond” symposium.

This symposium was of particular interest because of the unique combination of the latest research developments with the most up to date advances in clinical care for very-early-onset inflammatory bowel disease (VEO-IBD) and pediatric IBD, said course Co-director Judith R. Kelsen, MD, director of CHOP’s Very Early Onset Inflammatory Bowel Disease Clinic.

Read the rest of this entry >>

Jul 10 2018

Do Oral Antibiotics Play a Role in Kidney Stone Prevalence Increase in Youth?

The Findings: Children and adults treated with five classes of oral antibiotics have a significantly higher risk of developing kidney stones. The five classes include oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins. Patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones. For broad-spectrum penicillins, the increased risk was 27 percent higher. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics. The risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

Read the rest of this entry >>

Jun 18 2018

BWF Awards Recognize Young Investigators, Innovative Research

Read the rest of this entry >>

Mar 2 2018

Exploring the Wide World of the Microbiome

Studying the microbiome — the 40 trillion or so invisible microbes that call your body home — is like being an explorer of a secret world with its own language and lifeforms. Whether these microbes are sometimes friends or sometimes foe depends on subtle interactions with each other and the role of influential factors such as your genetics, environment, age, and diet.

The PennCHOP Microbiome Program awards annual pilot and feasibility grants to help faculty members of the University of Pennsylvania and Children’s Hospital of Philadelphia scientific communities navigate this uncharted territory. With the funding awarded in 2017, eight projects are underway, and CHOP clinician-scientists are leading two of them.

Read the rest of this entry >>

Aug 9 2016

“We’re Just Laughing About Poop”: A Clinical Research Study Experience Q&A

Clinical Research StudyNot every child who comes to the hospital is sick. Some of the families who visit The Children’s Hospital of Philadelphia on a regular basis are voluntary participants in research studies. Clinical research studies are an essential component of pediatric research that can lead to novel discoveries and advancements for populations in need.

Read the rest of this entry >>

Jul 5 2016

On Your Skin, In Your Gut, and All Around: A Microbiome Q&A

microbiomeMicrobes are on us and in us, and researchers are increasingly becoming aware that they are a vital part of us. Across The Children’s Hospital of Philadelphia and University of Pennsylvania a variety of research efforts are underway to understand these populations of bacteria, viruses, and other tiny life forms, known as the microbiome, and their impact on health.

Read the rest of this entry >>