This week’s In the News roundup takes science at The Children’s Hospital of Philadelphia to new elevations, including a stellar donation by the Eagles Charitable Foundation to support autism research. (Go Birds!)
Tag Archive: Genomics
Tiny bacteria facing a big fight, newborns in families getting help with financial challenges, and tiny DNA molecules having a big impact on medicine, were all in the news this week. Read on for more about these top stories in our weekly roundup of research news.
This week’s stories have elements that sound like fiction, but all are real, new scientific and medical findings: A condition that turns the body’s soft tissues into bone has new hope for a future treatment. Genetic superheroes walk among us, and they may not even know it. And pediatricians may have a tool to double their success in helping their patients’ parents quit smoking.
Poster Day at The Children’s Hospital of Philadelphia Research Institute is a tradition now in its 26th year. At this event, trainee-level researchers come together to present poster summaries of their work with the CHOP community.
A new $3.6 million grant from the National Institutes of Health’s Electronic Medical Records and Genomics (eMERGE) program will allow scientists at The Children’s Hospital of Philadelphia to not only uncover the genetic causes of autism and other pediatric conditions, but also to see how this information extends beyond the lab into patients’ electronic health records and improves care.
A new research opportunity under development as part of its Project:EveryChild, called Project:EveryChild Pediatric MATCH, aims to use the power of precision medicine to potentially provide investigational therapies for some children with advanced cancers.
New research from The Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania details how a diabetes-related gene functions on a biological pathway that affects the release of insulin.
After analyzing the DNA from thousands of patients, investigators from Children’s Hospital have uncovered several gene networks that may play important roles in autism.
A recent genomic study of neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene mutations — mutations that would suggest new targets for neuroblastoma treatment. Instead, the investigators have refocused on how neuroblastoma tumors evolve in response to medicine and other factors.
Genes provide tremendous information about how our bodies work and our possible predisposition for a variety of diseases and conditions. Researchers are working to discern what specific genes and gene regions play a role in disease.
The Children’s Hospital of Philadelphia played a major role in a recent international genetics study that found four new gene regions that contribute to low birth weight. In particular, the investigators found that three of those regions influence metabolism in adults and may play a role in adult height, the risk of type 2 diabetes, and adult blood pressure.