Tag Archive: gene

Feb 9 2016

CHOP Research Annual Report 2015: The Future Is Here — Don’t Miss It

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Scientific minds are imagining. Sophisticated machines are harnessing genetic data. An invisible universe of microbes is revealing new insights into disease. Discoveries are changing children’s worlds. Every second of every day is filled with wonder at The Children’s Hospital of Philadelphia Research Institute.

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Feb 19 2014

Study Leads to Increased Heart Disease Risk Understanding

Most of us have heard of the “good cholesterol” and “bad cholesterol” coursing through our bloodstream. In the conventional wisdom of the past 30 years, having more of the “good” variety — high-density lipoprotein, or HDL — can lower your risk of heart disease, while more “bad” cholesterol — low-density lipoprotein, or LDL — increases your risk.

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Jan 14 2014

Flipping a Gene Switch Reactivates Fetal Hemoglobin, May Reverse Sickle Cell Disease

Hematologists have long sought to reactivate fetal hemoglobin as a treatment for children and adults with sickle cell disease (SCD). Researchers at CHOP have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period.

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