Tag Archive: depression

May 17 2019

In the News: Early Investigator Award, Microbiome and Depression, INSAR 2019, Families’ Internet Searches, Telehealth Grant, and Pediatric Medical Devices

In this week’s news roundup, a Children's Hospital of Philadelphia researcher is recognized for her work to improve clinical effectiveness for children with endocrine-related diseases, and Center for Autism scientists present findings to the international autism research community. 

Other highlights include an investigation of the effects of the microbiome on the brain that could lead to novel treatments for psychiatric conditions, a look into Google searches as a mechanism to offer more tailored support and education to families with children newly diagnosed with cancer, and a funding boost for telehealth research. In addition, the CHOP-based Pennsylvania Pediatric Medical Device Consortium announced its latest seed grants to support the creation and development of medical devices designed for children. 

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Dec 18 2018

When Are Obsessive Compulsive Symptoms a Sign for Serious Psychiatric Conditions?

The findings:

Obsessive compulsive symptoms (OCS), which include intrusive thoughts, urges, mental images, and repetitive behaviors, are common in community youth. But while OCS are often considered developmentally appropriate, researchers in the Lifespan Brain Institute (LiBi) at Children’s Hospital of Philadelphia and the University of Pennsylvania have found that some OCS patterns – specifically bad intrusive thoughts – have stronger associations with serious psychiatric conditions such as depression, psychosis, and suicidal ideation. Other types of OCS, such as those surrounding cleaning or contamination, were not associated with major psychiatric conditions.

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Apr 16 2018

Researchers Target Brain Circuity as Driver of Antidepressant Behavior

Neurobiology researchers at Children’s Hospital of Philadelphia are looking deep into the brain’s circuitry to search for new avenues for the treatment of major depressive disorder, the most common mental illness.

In 2016, 10.3 million adults had at least one major depressive episode with severe impairment, according to the National Institute of Mental Health. While care by a health professional and antidepressant medication may be effective for some people, current treatments have a high rate of relapse and side effects.

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Mar 27 2018

Violence Prevention Initiative Reinforces How Research Helps to Keep Kids Safe

Editor’s Note: As part of a pediatric healthcare organization, the Violence Prevention Initiative (VPI) within the Research Institute addresses the antecedents to violence and supports an environment where children feel safe to learn, play, and develop. VPI accomplishes this by implementing hospital-wide and community-based programs, performing clinical research in bullying and violence prevention, providing trauma-informed trainings, and advocating for public policy changes that have implications for children and families.

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Oct 11 2017

Mind Meets Body in New Lupus Research: Q & A With Andrea Knight, Rheumatology Physician

When children have lupus, they often deal with more than just the physical burden of the autoimmune condition. Along with the swollen joints, skin rashes, ulcers, kidney disease and chest pain common to lupus, many of our pediatric patients also carry with them depression, anxiety, memory problems, and brain fog – all of which can adversely affect their school and social lives.

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Feb 12 2016

CHOP Research In The News: Teaching About Human Milk, Teen Depression

CHOP Research In the NewsImproving exclusive human milk feedings for NICU infants is a major public health issue in India, where Diane Spatz, PhD, RN-BC, FAAN, director of The Children’s Hospital of Philadelphia’s Breastfeeding and Lactation Program, spent two weeks teaching nurses and physicians about human milk and implementation of her 10 Step Model for Human Milk and Breastfeeding in Vulnerable Hospitals.

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Oct 22 2014

Investigators Study Orexins’ Role in Resilience to Stress

orexinWhy do some of us get stressed out while others seem to roll with life’s punches? That is the big question in the field of stress neurobiology, and to get closer to the answer, researchers at The Children’s Hospital of Philadelphia are exploring peptides called orexins as potential mediators of resilience or vulnerability to the effects of stress.

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