Tag Archive: craniosynostosis

Aug 31 2018

CHOP Leads Big Data Collaboration to Uncover Pathways Between Cancer and Birth Defects

When most of us think about cancer, a number of factors — from smoking, to sun exposure, to specific organs where a disorder develops — might jump to mind. But for Adam Resnick, PhD, co-founder of the Center for Data Driven Discovery and Biomedicine (D3B) at CHOP, in order to unravel the inextricable link between childhood cancer and other rare conditions, we must visualize pediatric cancer as a process.

As a single-cell zygote proliferates into a 37 trillion-cell being, something happens in the course of its development — a dysfunction, a deviance, a DNA-driven decision — that underpins not just the development of life-changing birth defects, but a potential vulnerability to childhood cancer as well.

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Apr 18 2017

Could Noninvasive Eye Imaging Safely Detect Elevated Intracranial Pressure, Without Surgery?

Taking light-wave images of the retina through a process called optical coherence tomography (OCT) shows promise as a safe, noninvasive way to identify elevated intracranial pressure (ICP) in children with subacute conditions such as tumors, hydrocephalus, or head trauma.

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