The cicadas may be “singing,” but the summer season isn’t over quite yet. In the midst of heat waves, drenching rainstorms, and vacation escapes, our investigators continue to advance scientific discovery. In this edition of In The News, Children’s Hospital of Philadelphia researchers report a more sensitive method of detecting genetic material delivered via adeno-associated viral vectors, while another group published findings that could help avoid unnecessary non-culture cerebrospinal fluid infection tests. Meanwhile, Petar Mamula, MD, looks into more effective management of a rare vascular anomaly, and Alex Fiks, MD, assumes a director role within the Research Institute.
Tag Archive: CPCE
Bigger isn’t always better, especially when it comes to combating pediatric infectious disease. Researchers conducted a study that compared the effectiveness of broad-spectrum antibiotic treatment to narrow-spectrum antibiotic treatment for common childhood acute respiratory tract infections (ARTIs). Children who received narrow-spectrum antibiotics had a higher health-related quality of life and a reduced risk of antibiotic side effects as compared to children receiving broad-spectrum antibiotics, according to data from this study.
Sometimes half is better than whole. That’s the idea behind a new multicenter study that Children’s Hospital of Philadelphia is participating in to compare a five-day (short) course of antibiotic therapy with a 10-day (standard) course of therapy to treat community-acquired pneumonia (CAP) in children.
This week’s In the News roundup takes science at The Children’s Hospital of Philadelphia to new elevations, including a stellar donation by the Eagles Charitable Foundation to support autism research. (Go Birds!)
The CPCE Pilot Grant Program offers funding opportunities twice a year to CHOP investigators conducting clinical effectiveness studies. The recipient of the Fall 2015 Pilot Grant Award was Nicolas Bamat, MD, and the two recipients of the Spring 2016 award were Sagori Mukhopadhyay, MD, MMSc, and David I. Chu, MD.
If scientific research were like building a house, pilot studies would be the foundation. Their purpose is to establish solid evidence that will attract external support for large-scale studies. The Center for Pediatric Clinical Effectiveness (CPCE) at The Children’s Hospital of Philadelphia is giving three investigators the tools that they need to get to start digging.
Winners chosen for the fall round of the CPCE’s Pilot Grant Program will focus on two projects that aim to have an impact on clinical decision-making.
As the new director of CHOP’s Center for Pediatric Clinical Effectiveness (CPCE), Theoklis Zaoutis, MD, MSCE, will do what he enjoys most — create, develop, and build new ideas.