Tag Archive: Center for Pediatric Clinical Effectiveness

Jul 10 2018

Do Oral Antibiotics Play a Role in Kidney Stone Prevalence Increase in Youth?

The Findings: Children and adults treated with five classes of oral antibiotics have a significantly higher risk of developing kidney stones. The five classes include oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins. Patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones. For broad-spectrum penicillins, the increased risk was 27 percent higher. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics. The risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

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Jun 20 2018

Researchers Head to Botswana to Study Antibiotic Use in Hospitalized Children

Eimear Kitt, MBBCh BAO

The tide of antibiotic resistance continues to rise worldwide, and it is taking Eimear Kitt, MBBCh BAO (Hons), a third-year fellow in Infectious Diseases, and her study team to Botswana in sub-Saharan Africa this summer to prospectively collect information on antibiotic use in hospitalized children. When they return to Children’s Hospital of Philadelphia and analyze their data, their findings will help to inform strategies to improve antibiotic stewardship in low- and middle-income settings.

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May 4 2018

Pediatric Academic Societies Meeting Packed With Discovery and Discussion

For many of our researchers, the annual Pediatric Academic Societies (PAS) Meeting is more than just another conference or convention: It’s an exciting and educational event filled with discovery and discussion about the myriad ways we can improve children’s health. This year, experts from Children’s Hospital of Philadelphia will convene in Toronto from May 5 to 8 for four days of networking, presentations, poster sessions, and awards. They’ll represent a range of pediatric fields — from behavioral health to bone health, injury research to emergency medicine, neonatology to autism spectrum disorder (ASD), and almost everything in between.

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Apr 3 2018

Broad vs. Narrow-spectrum Antibiotics: What's the Best Choice for Common Childhood Infections?

The Finding:

Bigger isn’t always better, especially when it comes to combating pediatric infectious disease. Researchers conducted a study that compared the effectiveness of broad-spectrum antibiotic treatment to narrow-spectrum antibiotic treatment for common childhood acute respiratory tract infections (ARTIs). Children who received narrow-spectrum antibiotics had a higher health-related quality of life and a reduced risk of antibiotic side effects as compared to children receiving broad-spectrum antibiotics, according to data from this study.

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Sep 6 2017

CPCE Putting Research Into Practice With Pilot Grant Program

As summer fades, it’s exciting to embrace a new season filled with vibrant opportunities. The Center for Pediatric Clinical Effectiveness at Children’s Hospital of Philadelphia is ushering in the fall with a call for applications to its Pilot Grant Program. The program aims to support CHOP investigators who are interested in conducting studies designed to gather evidence about novel strategies that could shift current research or a clinical practice paradigm.

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Aug 17 2017

Did a New App Facilitate Faster, Easier Dermatology Consults for Families?

Nobody enjoys sitting in a doctor’s waiting room, especially when they have an uncomfortable skin condition. A Children’s Hospital of Philadelphia study team tested a direct-to-consumer mobile app designed to facilitate routine dermatologic consultations for children and adolescents. The pilot study results showed the telemedicine technology was acceptable, easy to use, and expedited care.

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Feb 14 2017

CPCE Pilot Grant Awardees Want to Know: What Works Best?

CPCETwice a year, the CPCE Pilot Grant Program offers funding opportunities to CHOP investigators conducting clinical effectiveness studies. The recipient of the Fall 2016 Pilot Grant Awards are Ruth Abaya, MD, MPH; Yeh-Chung (Dan) Chang, MD; and Sheila Quinn, DO.

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Dec 20 2016

New Strategies Needed to Reduce Children’s Exposure to Antibiotics

antibioticsSometimes half is better than whole. That’s the idea behind a new multicenter study that Children’s Hospital of Philadelphia is participating in to compare a five-day (short) course of antibiotic therapy with a 10-day (standard) course of therapy to treat community-acquired pneumonia (CAP) in children.

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Dec 2 2016

CHOP Research In the News: Hypertension, Cancer Survivors’ Parents, Breastfeeding, Antibiotics, Allergies

CHOP Research In the NewsWelcome back to our regular roundup of research news from Children’s Hospital of Philadelphia! Now that we are bringing you these updates biweekly, we have an even richer collection of stories to share.

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Nov 15 2016

Q&A: How Pediatricians Can Help Suburban Families in Poverty

povertyThe shiny picture of the American dream sometimes belies underlying struggles. This may be especially true in suburban communities, where demographic shifts in the last decade have left growing numbers of families experiencing poverty or near-poverty conditions in which they struggle to pay the bills.

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