Tag Archive: Center for Mitochondrial and Epigenomic Medicine

Sep 21 2018

In the News: Brain Cancer Gene Therapy, 2019 Eagles Autism Challenge, Mitochondrial DNA in Cardiomyopathy, Kids First DRC, Device Symposium

Fall weather and football season have returned to us here at Children’s Hospital of Philadelphia Research Institute, bringing with them a fresh batch of research headlines. In this edition of our biweekly news roundup, catch up on the latest announcements for the second annual Eagles Autism Challenge, learn about new insights into the role mitochondrial DNA plays in heart disease progression, and stay updated on how CHOP helps to drive medical innovation and entrepreneurship forward in the Philadelphia community and beyond.

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Dec 27 2017

Our Most Read Stories of 2017 Bring Back the Wonder of Childhood

It was a big year for children’s health: We celebrated the U.S. Food and Drug Administration’s approval of the world’s first chimeric antigen receptor (CAR)-T cell therapy this September, followed closely by approval of the very first gene therapy to treat inherited blindness this month — both of which have their roots at Children’s Hospital of Philadelphia and the University of Pennsylvania. But besides the big headline-making breakthroughs (brilliant as they are), we wanted to know what other stories captivated our readers in 2017.

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Oct 3 2017

What Are Transcription Errors’ Role in Aging and Disease?

The human genome provides a precise, biological blueprint of life. To implement this blueprint correctly, the genome must be read with great precision, but it’s impossible for this process to be completely error-free. Mistakes during transcription — random errors in how DNA sequences are copied for a gene to be expressed — can happen any time in any number of ways.

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Aug 23 2017

Mitochondrial Gene Defects Associated With Autism Traced Back to Ancient Times

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.

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Jun 21 2017

Dr. Douglas Wallace Honored for Passion, Creativity in Biomedical Research

Doug WallaceLike the mitochondria that Douglas Wallace, PhD, has dedicated his scientific career to studying, energy keeps building about his exciting work. Dr. Wallace’s latest high-profile achievement is being selected as the recipient of the Dr. Paul Janssen Award for Biomedical Research.

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Oct 21 2016

CHOP Research In the News: Cancer Moonshot Yields Data-Sharing Initiatives, Hemophilia Surprise, Mitochondrial Medal

CHOP Research In the NewsBuckle your seatbelts because this has been a busy week for research news at Children’s Hospital of Philadelphia.

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Jun 7 2016

Lots to Cheer About in Bench to Bedside

Bench to BedsideYippee! Hooray! Woo-hoo! We’d like to take a few moments to celebrate the recent accolades given to scientists and physician researchers at The Children’s Hospital of Philadelphia Research Institute who are featured in the latest issue of Bench to Bedside, our monthly newsmagazine.

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May 27 2016

CHOP Research In the News: Summer-Ready Stories about Families, Travel, and Science

CHOP Research In the NewsWelcome back to another weekly roundup of research news from The Children’s Hospital of Philadelphia! As we head into Memorial Day weekend in the U.S. and the informal start to summer, let’s begin with news this week that resonates with some of the things we love about summer.

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May 17 2016

Bringing Science to Life at the Philadelphia Science Festival

Philadelphia Science FestivalWhat happens when you combine curiosity, families, and science and technology? You’d know the answer to that question and lots more if you attended the Philadelphia Science Festival, a massive science carnival held over nine days featuring hands-on experiments and demonstrations that showcased how science connects to our everyday lives.

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