We’re sailing into the middle of June with yet another set of exciting headlines, from the fundraising results of this the 2019 Eagles Autism Challenge, to two new awards that support researchers in our Cancer Center at Children’s Hospital of Philadelphia, to novel insights into mental health after a serious injury, and to discoveries about the impact of trauma and poverty on brain development. Read on for the latest CHOP research news!
Tag Archive: Center for Injury Research and Prevention
By Nancy McCann
Happy unofficial start to summer 2019! If you find yourself looking for something good to read on the beach, in the backyard, or floating on a boat, here you go. Discover which Children’s Hospital of Philadelphia docs and researchers have been in the news recently. We’re covering the risk of repeat concussions, a best method to screen for food insecurity, and a newly discovered causative gene for severe childhood epilepsy.
Whether they study helmets on the football field or hemophilia in a lab, our scientists at Children’s Hospital of Philadelphia Research Institute are always on the cutting-edge of their respective fields, as the latest roundup of research news shows. This week, read about what to expect at next week’s Pediatric Academic Societies Meeting, discover how a CHOP engineer is helping to make the NFL safer, and learn about new results from our Center for Fetal Research about treating lung diseases in utero.
In this week’s news roundup, there’s a lot to be proud of as our researchers make impactful discoveries, such as new-found variability in a mitochondrial disease-causing gene and encouraging findings about an antibody-drug conjugate that targets a surface protein expressed in childhood neuroblastomas, effectively killing cancer cells. Wanjiku Njoroge, MD, and colleagues followed mothers of very preterm infants to determine stress in the NICU and its effects five years later, and Allison Curry, PhD, MPH, is changing perceptions about visually impaired drivers.
Persevere, persist, and prioritize. These are some of the powerful words of wisdom that women in science at Children’s Hospital of Philadelphia would like to share with the next generation of female scientists. To celebrate Women’s History Month this year, we are continuing our tradition of highlighting the talented researchers at CHOP who work in the science, engineering, math, and technology (STEM) fields, which have historically been underrepresented by women.
This week, we highlight the results of innovation powered by collaboration, within Children’s Hospital of Philadelphia Research Institute and around the globe. A multicenter, international consortium revealed genes newly linked to epilepsy, while CHOP CEO Madeline Bell visited Dubai for an interchange of knowledge and technology at the largest medical conference in the world. Closer to home, the Children’s Hospitals’ Solutions for Patient Safety Network, comprised of 135 hospitals in the United States, published its findings on the most effective targets for pediatric patient safety research, and a high school intern helped researchers recruit participants for a teen driving study. Learn about the latest trends in pediatric opioid prescription, and get an update on the Delaney family, whose conjoined twin daughters were separated with painstaking care by a multidisciplinary team at CHOP.
As the new year approaches, we look back with gratitude for yet another year packed with scientific breakthroughs in children’s health. Continuing a remarkable run for personalized gene therapies, 2018 marked the European Commission’s approval of two gene therapies pioneered at Children’s Hospital of Philadelphia and the University of Pennsylvania, as patients in the European Union (EU) may now be treated with chimeric antigen receptor (CAR)-T cell therapy for aggressive forms of leukemia, and the very first gene therapy developed for inherited blindness.
When young investigators bring big ideas to Kristy Arbogast, PhD, this year’s winner of the Award for Excellence in Mentoring Research Trainees, she is eager to help them figure out their research vision from the ground up. That’s because Dr. Arbogast knows firsthand the value early career mentors have in shaping how investigators learn to interrogate a scientific problem, analyze the data, and use the results to improve the world.
In 1997, researchers at Children’s Hospital of Philadelphia partnered with State Farm Insurance, one of the largest automobile insurance companies in the U.S., to create the nation’s first large-scale, child-focused crash surveillance system. Over the next 10 years, the Partners for Child Passenger Safety Program (PCPS) studied more than 875,000 children involved in 600,000 car crashes, conducted 33,000 in-depth interviews, and analyzed over 800 on-site investigations. By its close in 2007, the world’s largest study of children in crashes had produced a robust set of recommendations based on hard data and backed by scientific expertise that would shape and advance legislation, vehicle design, and public health education for years to come. Since PCPS began, the U.S.
About 50 percent of parents reported talking on their cell phones while driving with their young child in the vehicle, while one in three read text messages, and one in seven used social media, according to online surveys of adults across the U.S. The findings, published in a recent study from our Center for Injury Research and Prevention (CIRP) at Children’s Hospital of Philadelphia and the University of Pennsylvania School of Nursing, also reveal that parents who used their cell phones in the car were more likely to engage in other risky driving behaviors, such as not wearing a seat belt when they were a driver and not consistently using their typical child restraint system (CRS) for their child.