It was a big year for children’s health: We celebrated the U.S. Food and Drug Administration’s approval of the world’s first chimeric antigen receptor (CAR)-T cell therapy this September, followed closely by approval of the very first gene therapy to treat inherited blindness this month — both of which have their roots at Children’s Hospital of Philadelphia and the University of Pennsylvania. But besides the big headline-making breakthroughs (brilliant as they are), we wanted to know what other stories captivated our readers in 2017.
Tag Archive: Center for Autism Research
Notable awards, new autism initiatives, and a novel approach to managing sickle cell disease are all part of this week’s roundup of research news.
September marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research. Oncology investigators at CHOP also got a big boost in research funding from Hyundai’s nonprofit organization, Hope on Wheels. And that’s only the beginning: Since September marks the return of the football season, we’re thrilled to share the latest headlines on how the National Football League (NFL) is helping to drive concussion research.
A tantrum, a kick, a meltdown: In school-age children with autism, these aggressive and oppositional behaviors – described collectively as “challenging behaviors” – are some of the biggest struggles reported by parents and teachers. New research from the Center for Autism Research (CAR) at Children’s Hospital of Philadelphia suggests that these behaviors arise when children don’t have the skills they need to cope with situations or problems in an adaptive and healthy way. Working on skills such as emotion regulation, impulse control, cognitive inflexibility, and others that the researchers identified may be a helpful approach.
Every good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.
Recognizing that physicians must navigate such a wide variation of family values, expectations, and priorities, Susan Levy, MD, MPH, a developmental pediatrician and researcher for the Center for Autism Research at Children’s Hospital of Philadelphia, co-authored an American Academy of Pediatrics (AAP) clinical report on behalf its Council on Children with Disabilities to provide a framework for the implementation of shared decision-making.
A neuroimaging scan at age 6 months may accurately predict autism spectrum disorder (ASD) among high-risk infants. The infants were considered to be at high risk because they had older siblings with ASD. Overall, the study team found 974 functional connections in the 6-month-olds’ brains that were associated with autism-related behaviors.
Our researchers whose work is at the cross section between injury and neurodevelopmental or intellectual disabilities have a unique vantage point when studying the driving safety of adolescents with autism spectrum disorder (ASD). The Research Institute is home to two of the most highly regarded autism and pediatric injury research centers in the world.
One in three adolescents with autism spectrum disorder (ASD) acquires an intermediate driver’s license, and the majority does so in their 17th year. An intermediate license permits drivers to travel with restrictions, such as driving curfews and limits on the number of passengers.
In times of uncertainty, a dose of positive news reminds us that making progress through difficult situations is possible — our Children’s Hospital of Philadelphia research community does it every day!