More than six years after Emily Whitehead became the first child to receive chimeric antigen receptor (CAR) T-cell therapy, doctors have had remarkable success in turning the immune systems of even more children with acute lymphoblastic leukemia (ALL) into top-notch fighters against the disease. For some patients, however, these superhero T-cells still fail in their mission to find and fight their cancer targets.
Tag Archive: bioinformatics
The Human Genome Project’s successful completion 15 years ago gave us a new genomic lens to read our 20,000 or so protein-coding genes. Since then, a surge in next-generation sequencing technologies is generating new insights daily that sharpen our view of how the human genome works.
Yi Xing, PhD, was on the cusp of this revolution in medicine as he finished his PhD training in molecular biology and bioinformatics at University of California Los Angeles (UCLA). His research career began to rise during the incredible takeoff of big data science, and he became a prominent scientist in this cutting-edge field. The immense challenges of synthesizing diverse data sets from many sources come with vast opportunities to change pediatric medicine, which is why Dr. Xing is eager to assume his new role as the inaugural director of the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia.
The Symposium on Advances in Genomics, Epidemiology and Statistics (SAGES) has a winning formula for success: Bring together an interdisciplinary group of scientists who are all working toward the same goal of understanding the genetic basis of human disorders. Close to 200 SAGES attendees gathered June 1 at the Smilow Center for Translational Research for a dynamic opportunity to explore a wealth of ideas and make connections with colleagues from diverse areas of expertise.
This week we’re excited to report on a second award for an innovative technology solution to access, filter, and harness emerging disease updates.
Welcome back to another weekly roundup of research news from The Children’s Hospital of Philadelphia! As we head into Memorial Day weekend in the U.S. and the informal start to summer, let’s begin with news this week that resonates with some of the things we love about summer.
Dr. Tan, a cancer genomics and bioinformatics researcher, joined The Children’s Hospital of Philadelphia in January. Within weeks of his arrival, Vice President Joe Biden launched the cancer “moonshot” initiative during a visit with cancer researchers from the University of Pennsylvania and CHOP at Penn’s Abramson Cancer Center.