In this edition of In the News, learn about digital medicine and what it means for children with autism spectrum disorder and co-occurring attention deficit/hyperactivity disorder (ADHD). Read about a variation in care study, a recent FDA approved drug treatment for a specific childhood cancer, and why two Children’s Hospital of Philadelphia researchers are calling for improved pediatric palliative care measures. And lastly, join us in celebrating the addition of six new initiatives to CHOP’s Frontier Programs.
Tag Archive: Benjamin Yerys
Summer at Children’s Hospital of Philadelphia is definitely off to a sweet start: We kick off this week’s research roundup with a new way of thinking about honey (thanks to novel findings from our ear, nose, and throat specialists) and congratulate the Cancer Center at CHOP on yet another successful day of serving up lemonade to support the Alex’s Lemonade Stand Foundation (ALSF). On top of that, we cover research updates from our Mitochondrial Medicine Frontier Program and the Center for Autism Research (CAR), and share a special new award for Stephan Grupp, MD, PhD, director of the Cancer Immunotherapy Program.
In a new study that sheds light on a longstanding paradox in autism research, investigators showed how children and teens with autism spectrum disorder (ASD) can have both stronger and weaker brain connections than their typically developing peers. Resting-state functional magnetic resonance imaging (fMRI) revealed that while individuals with ASD have weaker brain connections compared to their peers overall (a measure known as absolute connectivity), they simultaneously exhibited stronger connections within the brain networks implicated in attention and social cognition compared to their other networks (a measure known as relative connectivity). Additionally, the more these brain connections differed from typical development, the more severe the child’s ASD symptoms seemed to be.
Every good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.
Our researchers whose work is at the cross section between injury and neurodevelopmental or intellectual disabilities have a unique vantage point when studying the driving safety of adolescents with autism spectrum disorder (ASD). The Research Institute is home to two of the most highly regarded autism and pediatric injury research centers in the world.
One in three adolescents with autism spectrum disorder (ASD) acquires an intermediate driver’s license, and the majority does so in their 17th year. An intermediate license permits drivers to travel with restrictions, such as driving curfews and limits on the number of passengers.
This week’s stories from The Children’s Hospital of Philadelphia include the use of big data to understand a tiny molecular mechanism central to how cells function, a clinical trial of video games for improving attention, and the neurodevelopmental effects of so-called “smart drugs.”