Tag Archive: Autism Spectrum Disorder

Jan 11 2018

Is Autism Associated With Stronger or Weaker Brain Connections?

The Finding:

In a new study that sheds light on a longstanding paradox in autism research, investigators showed how children and teens with autism spectrum disorder (ASD) can have both stronger and weaker brain connections than their typically developing peers. Resting-state functional magnetic resonance imaging (fMRI) revealed that while individuals with ASD have weaker brain connections compared to their peers overall (a measure known as absolute connectivity), they simultaneously exhibited stronger connections within the brain networks implicated in attention and social cognition compared to their other networks (a measure known as relative connectivity). Additionally, the more these brain connections differed from typical development, the more severe the child’s ASD symptoms seemed to be.

Read the rest of this entry >>

Jan 5 2018

Researchers Take Gaming to a New Level to Help Children With Autism

Each new year comes with anticipation for the latest and greatest in the world of video games to be revealed. Which sequels will surpass their originals? Will beloved characters be reinvented? And we want to know: What brand-new entries are lined up that could offer an amazing experience in field of gaming for health?

The Center for Autism Research (CAR) at Children’s Hospital of Philadelphia has several studies in the works that are looking at the feasibility of using video games and virtual reality to help children improve symptoms of autism. With engaging platforms and cutting-edge graphics, these games are aiming for a “high score” as easy-to-access, affordable, and effective interventions for autism spectrum disorder (ASD). Here’s a quick glance at what is on the horizon:

Read the rest of this entry >>

Dec 27 2017

Our Most Read Stories of 2017 Bring Back the Wonder of Childhood

It was a big year for children’s health: We celebrated the U.S. Food and Drug Administration’s approval of the world’s first chimeric antigen receptor (CAR)-T cell therapy this September, followed closely by approval of the very first gene therapy to treat inherited blindness this month — both of which have their roots at Children’s Hospital of Philadelphia and the University of Pennsylvania. But besides the big headline-making breakthroughs (brilliant as they are), we wanted to know what other stories captivated our readers in 2017.

Read the rest of this entry >>

Oct 6 2017

Neuroblastoma Gene Variants, Center for GI Motility Expansion, Improving Autism Diagnosis, Fontan Procedure Follow-Ups

CHOP Research In the NewsThis week, new research findings at Children’s Hospital of Philadelphia are propelling the way we think about autism, single ventricle survivors, and neuroblastoma forward, as our investigators continued to push the boundaries of what we know.

Read the rest of this entry >>

Sep 22 2017

AAP Conference, PCORI Sickle Cell Research, Eagles Autism Challenge, Anxiety and Autism, New Immunotherapy Target for Neuroblastoma

CHOP Research In the NewsNotable awards, new autism initiatives, and a novel approach to managing sickle cell disease are all part of this week’s roundup of research news.

Read the rest of this entry >>

Sep 5 2017

What Leads to Challenging Behaviors in Children with Autism?

snapshot science

The Findings:

A tantrum, a kick, a meltdown: In school-age children with autism, these aggressive and oppositional behaviors – described collectively as “challenging behaviors” – are some of the biggest struggles reported by parents and teachers. New research from the Center for Autism Research (CAR) at Children’s Hospital of Philadelphia suggests that these behaviors arise when children don’t have the skills they need to cope with situations or problems in an adaptive and healthy way. Working on skills such as emotion regulation, impulse control, cognitive inflexibility, and others that the researchers identified may be a helpful approach.

Read the rest of this entry >>

Jun 30 2017

Measuring Flexible Thinking, Managing Concussions, Tech Addiction, 2017 Pew Scholar, U.S. News & World Report

CHOP Research In the NewsEvery good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.

Read the rest of this entry >>

Jun 27 2017

Let’s Talk: A Q&A About How to Engage in Shared Decision-making

susan_levy_cropRecognizing that physicians must navigate such a wide variation of family values, expectations, and priorities, Susan Levy, MD, MPH, a developmental pediatrician and researcher for the Center for Autism Research at Children’s Hospital of Philadelphia, co-authored an American Academy of Pediatrics (AAP) clinical report on behalf its Council on Children with Disabilities to provide a framework for the implementation of shared decision-making.

Read the rest of this entry >>

Jun 9 2017

Could a Single Brain Scan Predict Autism Among High-risk Infants?

A neuroimaging scan at age 6 months may accurately predict autism spectrum disorder (ASD) among high-risk infants. The infants were considered to be at high risk because they had older siblings with ASD. Overall, the study team found 974 functional connections in the 6-month-olds’ brains that were associated with autism-related behaviors.

Read the rest of this entry >>

May 3 2017

We Push the Boundaries of Science When Research Fields Intersect

Our researchers whose work is at the cross section between injury and neurodevelopmental or intellectual disabilities have a unique vantage point when studying the driving safety of adolescents with autism spectrum disorder (ASD). The Research Institute is home to two of the most highly regarded autism and pediatric injury research centers in the world.

Read the rest of this entry >>