Tag Archive: ASD

Apr 18 2018

Center for Autism Research a Proving Ground for Novel Approaches

Editor’s Note: Each year, 10,000 patients diagnosed with autism spectrum disorder (ASD) visit a wide range of clinical programs at Children’s Hospital of Philadelphia — including developmental pediatrics, child and adolescent psychiatry, neurology, psychology, speech and language therapy, clinical genetics, general pediatrics, and more. With this enormous patient base and broad sets of expertise across specialties, the Center for Autism Research (CAR) at CHOP offers a tremendous opportunity to conduct rigorous research with its ultimate aim being to improve care, quality of life and long-term outcomes for individuals with ASD.

Read the rest of this entry >>

Feb 1 2018

Join Our Team to Tackle Autism Spectrum Disorder Research

With the entire city soaring from the Eagles Championship win, we can feel even better that our home team also has a heart for research. So take your Eagles fandom to the next level by joining your colleagues, patients, friends, and family on Team CHOP Research in the Eagles Autism Challenge. Not only will you help fund breakthroughs made right here at Children’s Hospital of Philadelphia for the thousands of children and families who are affected by autism, but you will have the opportunity to celebrate on the field with the NFC Champions themselves!

Read the rest of this entry >>

Jan 11 2018

Is Autism Associated With Stronger or Weaker Brain Connections?

The Finding:

In a new study that sheds light on a longstanding paradox in autism research, investigators showed how children and teens with autism spectrum disorder (ASD) can have both stronger and weaker brain connections than their typically developing peers. Resting-state functional magnetic resonance imaging (fMRI) revealed that while individuals with ASD have weaker brain connections compared to their peers overall (a measure known as absolute connectivity), they simultaneously exhibited stronger connections within the brain networks implicated in attention and social cognition compared to their other networks (a measure known as relative connectivity). Additionally, the more these brain connections differed from typical development, the more severe the child’s ASD symptoms seemed to be.

Read the rest of this entry >>

Jan 5 2018

Researchers Take Gaming to a New Level to Help Children With Autism

Each new year comes with anticipation for the latest and greatest in the world of video games to be revealed. Which sequels will surpass their originals? Will beloved characters be reinvented? And we want to know: What brand-new entries are lined up that could offer an amazing experience in field of gaming for health?

The Center for Autism Research (CAR) at Children’s Hospital of Philadelphia has several studies in the works that are looking at the feasibility of using video games and virtual reality to help children improve symptoms of autism. With engaging platforms and cutting-edge graphics, these games are aiming for a “high score” as easy-to-access, affordable, and effective interventions for autism spectrum disorder (ASD). Here’s a quick glance at what is on the horizon:

Read the rest of this entry >>

Aug 23 2017

Mitochondrial Gene Defects Associated With Autism Traced Back to Ancient Times

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.

Read the rest of this entry >>

Jun 27 2017

Let’s Talk: A Q&A About How to Engage in Shared Decision-making

susan_levy_cropRecognizing that physicians must navigate such a wide variation of family values, expectations, and priorities, Susan Levy, MD, MPH, a developmental pediatrician and researcher for the Center for Autism Research at Children’s Hospital of Philadelphia, co-authored an American Academy of Pediatrics (AAP) clinical report on behalf its Council on Children with Disabilities to provide a framework for the implementation of shared decision-making.

Read the rest of this entry >>

Jun 9 2017

Could a Single Brain Scan Predict Autism Among High-risk Infants?

A neuroimaging scan at age 6 months may accurately predict autism spectrum disorder (ASD) among high-risk infants. The infants were considered to be at high risk because they had older siblings with ASD. Overall, the study team found 974 functional connections in the 6-month-olds’ brains that were associated with autism-related behaviors.

Read the rest of this entry >>

May 3 2017

We Push the Boundaries of Science When Research Fields Intersect

Our researchers whose work is at the cross section between injury and neurodevelopmental or intellectual disabilities have a unique vantage point when studying the driving safety of adolescents with autism spectrum disorder (ASD). The Research Institute is home to two of the most highly regarded autism and pediatric injury research centers in the world.

Read the rest of this entry >>

Apr 25 2017

Do Teens With Autism Get Their Driver’s License?

One in three adolescents with autism spectrum disorder (ASD) acquires an intermediate driver’s license, and the majority does so in their 17th year. An intermediate license permits drivers to travel with restrictions, such as driving curfews and limits on the number of passengers.

Read the rest of this entry >>

Feb 24 2017

CHOP Research In the News: Predicting Autism, Rear Seat Safety, Hypoplastic Left Heart Syndrome, Pediatric Stroke

CHOP Research In the NewsThis week’s In the News highlights remind us of one of our favorite quotes from Helen Keller: “Alone we can do so little; together we can do so much.” Read on to see how researchers from Children’s Hospital of Philadelphia are working with different groups who share the same vision and scientific goals to advance pediatric care.

Read the rest of this entry >>