Tag Archive: Adam Resnick

Sep 21 2018

In the News: Brain Cancer Gene Therapy, 2019 Eagles Autism Challenge, Mitochondrial DNA in Cardiomyopathy, Kids First DRC, Device Symposium

Fall weather and football season have returned to us here at Children’s Hospital of Philadelphia Research Institute, bringing with them a fresh batch of research headlines. In this edition of our biweekly news roundup, catch up on the latest announcements for the second annual Eagles Autism Challenge, learn about new insights into the role mitochondrial DNA plays in heart disease progression, and stay updated on how CHOP helps to drive medical innovation and entrepreneurship forward in the Philadelphia community and beyond.

Read the rest of this entry >>

Aug 31 2018

CHOP Leads Big Data Collaboration to Uncover Pathways Between Cancer and Birth Defects

When most of us think about cancer, a number of factors — from smoking, to sun exposure, to specific organs where a disorder develops — might jump to mind. But for Adam Resnick, PhD, co-founder of the Center for Data Driven Discovery and Biomedicine (D3B) at CHOP, in order to unravel the inextricable link between childhood cancer and other rare conditions, we must visualize pediatric cancer as a process.

As a single-cell zygote proliferates into a 37 trillion-cell being, something happens in the course of its development — a dysfunction, a deviance, a DNA-driven decision — that underpins not just the development of life-changing birth defects, but a potential vulnerability to childhood cancer as well.

Read the rest of this entry >>

Jul 6 2018

Eaise Family Rallies for Brain Tumor Research

Debbie Eaise remembers the day her 18-year-old son, Kevin, walked onto the University of Pennsylvania campus where he is set to play for the Penn Quakers baseball team this fall. From Meiklejohn Stadium, Penn’s home field, you can pitch a baseball and reach Children’s Hospital of Philadelphia, said Debbie — a proximity so palpable that she could see the change in her son’s face and sense his comfort level at ease while he toured his future school.

As her husband, Kevin Sr., and others have noted, Kevin has come full circle. It was right there on the Penn-CHOP campus, after all, with its skyline of medical buildings, that Kevin and his family’s life changed inextricably, ushering in what Debbie describes as their “new normal.”

Read the rest of this entry >>

May 24 2018

Collaborative Discovery Supports Next Wave of Pediatric Brain Tumor Innovation

Editor’s Note: Childhood brain tumors remain some of the most difficult to treat cancers, especially because of current therapies’ long-term side effects for the survivors. In honor of Brain Tumor Awareness Month, Adam Resnick, PhD, director of the Center for Data-Driven Discovery in Biomedicine (D3b) at Children’s Hospital of Philadelphia, is our guest blogger. He brings us up to date on how the CHOP-led consortia, working with patients, families, and partnering institutions, has witnessed first-in-kind initiatives and innovative clinical trials aimed at personalized, precision-based approaches for brain tumors that are redefining the scientific landscape of research and therapeutic translation.

Read the rest of this entry >>

Feb 28 2018

Better Biobanking a Best Bet for Rare Disease Research

Editor’s Note: Families facing a rare disease diagnosis often do not know where to turn first in their search for the most advanced treatments and potentially a cure for their children. Only 5 percent of rare diseases have a treatment approved by the Food and Drug Administration, according to the National Organization for Rare Disorders. This is due in part to the lack of high quality biospecimens for research.

Read the rest of this entry >>

Nov 3 2017

Weight and CHD, Tumor Biology, I-ACT Grant, Mitochondrial Disease Guidelines

As the November chill settles in, warm up to new scientific discoveries and novel projects for improving children’s health from our researchers at Children’s Hospital of Philadelphia. In our roundup of research headlines, we share the latest findings on the biology of pediatric low-grade gliomas – the most common childhood brain tumor – congratulate Christopher Forrest, MD, in his role as co-investigator of a new FDA-funded clinical trials network, and give you the highlights on two new papers from researchers in mitochondrial medicine and cardiology.

Read the rest of this entry >>

Jun 2 2017

Good Morning America, Roberts Center Grand Opening, Center for Thoracic Insufficiency Reunion, Healthcare Innovator Award, Dragon Master Foundation

CHOP Research In the NewsOnwards and upwards: Last week’s grand opening of the new Roberts Center for Pediatric Research coincided with a series of exciting news that suggest breakthroughs are on the horizon.

Read the rest of this entry >>

Oct 21 2016

CHOP Research In the News: Cancer Moonshot Yields Data-Sharing Initiatives, Hemophilia Surprise, Mitochondrial Medal

CHOP Research In the NewsBuckle your seatbelts because this has been a busy week for research news at Children’s Hospital of Philadelphia.

Read the rest of this entry >>

Feb 25 2016

CHOP Big Data Center Visits White House for Precision Medicine Summit

precision medicineToday at the White House, President Obama welcomed guests, including Adam Resnick, PhD, representing The Children’s Hospital of Philadelphia, for a morning of remarks and discussions about what the Precision Medicine Initiative (PMI) has achieved to date, and how it can take the next steps into the new era of medicine that delivers the right treatment at the right time to the right person.

Read the rest of this entry >>

Feb 5 2016

CHOP Research In the News: Triple-Threat Cancer Gene, Autism and Faces

CHOP Research In the NewsCancer genetics and collaboration were big themes in this week’s news featuring research at The Children’s Hospital of Philadelphia. Check out our weekly summary of some of the developments this first week of February.  

Read the rest of this entry >>