More than six years after Emily Whitehead became the first child to receive chimeric antigen receptor (CAR) T-cell therapy, doctors have had remarkable success in turning the immune systems of even more children with acute lymphoblastic leukemia (ALL) into top-notch fighters against the disease. For some patients, however, these superhero T-cells still fail in their mission to find and fight their cancer targets.
Tag Archive: acute lymphoblastic leukemia
If you’re looking for a spark of inspiration during January’s long and sometimes dreary days, don’t miss this week’s roundup of headlines from in and around Children’s Hospital of Philadelphia Research Institute. Our scientists’ passionate work in the lab found a spotlight in the mainstream media as “TODAY” featured how our stem cell research can help today’s cancer survivors become tomorrow’s parents. Meanwhile, eye-opening findings from the Lifespan Brain Institute (LiBi) sparked a wider conversation about how pediatricians and parents can stay alert for suicidal thoughts in teens. In more news, a recent study highlighted the need for more antibiotic stewardship in non-children’s hospitals, while a successful device consortium based at CHOP officially became a statewide affair.
Along with the start of school and settling into new routines, September marks Childhood Cancer Awareness Month: a special time to support cancer research and care for patients and families impacted by the disease. Fittingly, this week’s roundup of research news highlights the remarkable impact our oncologists have made for children with cancer around the world. And on top of that, we highlight new findings that challenge the traditional notion of the teen years as a reckless time of risky behavior.
Stephen P. Hunger, MD, has received numerous honors throughout his decorated career. However, winning the George R. Buchanan Lectureship Award from the American Society of Pediatric Hematology/Oncology (ASPHO) had particularly special meaning to the chief of the Division of Oncology and director of the Center for Childhood Cancer Research at Children’s Hospital of Philadelphia.
Recognized internationally in the field of pediatric leukemia clinical care and research, Dr. George R. Buchanan— past president of ASPHO and a renowned pediatric hematology physician-researcher — was very supportive of Dr. Hunger early in his career.
Cars, computational biology, and cancer advances are all featured in this week’s roundup of Children’s Hospital of Philadelphia research news, as our investigators received recognition at places as far as the New York International Auto Show, and as close as our hospital’s own Seacrest Studios. Read on to learn more about new awards from Hyundai’s nonprofit organization, Hope on Wheels, the Emily Whitehead Foundation’s generous gift to our Cancer Immunotherapy Frontier Program, and more!
From the discovery of stem cells that multiply after a lung injury, to new data that advances how we think about (and treat) childhood cancer, our first roundup of March is packed with discovery. Read on to learn how our researchers stay at the forefront of pediatric science with a new study that expands what scientists know about the body’s extraordinary ability to regenerate, a pan-cancer project that distinguishes how cancer develops in children versus adults, and a handful of updates on what our investigators have in store for the near future.
We’re finishing off the week with a winning touchdown of news that gives us as much pride for our researchers as we have for our Philadelphia Eagles in Sunday’s Super Bowl. In this roundup of recent headlines, we cover new results from the game-changing immunotherapy for acute lymphoblastic leukemia (ALL) pioneered by Children’s Hospital of Philadelphia and University of Pennsylvania scientists, announce a generous family donation that will benefit research at our Leukodystrophy Center of Excellence, and share new awards and advances from our talented investigators and clinicians.
September marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research. Oncology investigators at CHOP also got a big boost in research funding from Hyundai’s nonprofit organization, Hope on Wheels. And that’s only the beginning: Since September marks the return of the football season, we’re thrilled to share the latest headlines on how the National Football League (NFL) is helping to drive concussion research.
Our latest research news roundup carries a hint of summer and exciting new beginnings.
“Bold” is perhaps the best word to describe this week’s roundup of Research Institute news, as Children’s Hospital of Philadelphia nurses and investigators alike made headlines for their experimental work in pediatric CAR T-cell therapy.