Tag Archive: Yi Xing

May 29 2019

2019 Scientific Symposium Sparks Discussions on Big Data

By Jillian Rose Lim, Barbara Drosey, Sharlene George, and Nancy McCann

Researchers exchanged big ideas about big data at the 2019 Scientific Symposium, an event that brought together the bright minds of our Children’s Hospital of Philadelphia research community. A lineup of thought-provoking speakers from CHOP and the University of Pennsylvania shared presentations corresponding with the symposium’s themes, “Big Data” and “Today’s Discoveries and Tomorrow’s Possibilities.” 

“The goal [of this symposium] is to highlight the tremendous advances by CHOP investigators in the booming fields of computational biology, data science, and genomics,” said Yi Xing, PhD, chair of the event and director of the Center for Computational and Genomic Medicine at CHOP. 

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Mar 4 2019

New Computational Method Sheds Light on How Genetic Variants Alter RNA Processing

By Sharlene George

A key moment occurs in any gripping novel that sets in motion the characters’ doom or fortune. In the context of gene regulation, RNA-binding proteins (RBPs) play a similar pivotal role determining ribonucleic acid molecules’ (RNAs’) fate by guiding post-transcriptional events. This process is essential to interpretation of genetic code and its function in protein synthesis, which are the building blocks of any organism.

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Dec 31 2018

Our Most Read Stories of 2018 Celebrate Diversity, Data, and Discovery

As the new year approaches, we look back with gratitude for yet another year packed with scientific breakthroughs in children’s health. Continuing a remarkable run for personalized gene therapies, 2018 marked the European Commission’s approval of two gene therapies pioneered at Children’s Hospital of Philadelphia and the University of Pennsylvania, as patients in the European Union (EU) may now be treated with chimeric antigen receptor (CAR)-T cell therapy for aggressive forms of leukemia, and the very first gene therapy developed for inherited blindness.

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Nov 13 2018

New Center for Computational and Genomic Medicine Harnesses Technology and Big Data for Discovery

The Human Genome Project’s successful completion 15 years ago gave us a new genomic lens to read our 20,000 or so protein-coding genes. Since then, a surge in next-generation sequencing technologies is generating new insights daily that sharpen our view of how the human genome works.

Yi Xing, PhD, was on the cusp of this revolution in medicine as he finished his PhD training in molecular biology and bioinformatics at University of California Los Angeles (UCLA). His research career began to rise during the incredible takeoff of big data science, and he became a prominent scientist in this cutting-edge field. The immense challenges of synthesizing diverse data sets from many sources come with vast opportunities to change pediatric medicine, which is why Dr. Xing is eager to assume his new role as the inaugural director of the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia.

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Apr 20 2018

Emily Whitehead Anniversary, Buchanan Lectureship, Hyundai Young Investigators, Yi Xing, New York Auto Show

Cars, computational biology, and cancer advances are all featured in this week’s roundup of Children’s Hospital of Philadelphia research news, as our investigators received recognition at places as far as the New York International Auto Show, and as close as our hospital’s own Seacrest Studios. Read on to learn more about new awards from Hyundai’s nonprofit organization, Hope on Wheels, the Emily Whitehead Foundation’s generous gift to our Cancer Immunotherapy Frontier Program, and more!

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