Tag Archive: Princeton University

Jun 7 2019

Fusing Computational Genomics and Functional Genomics To Elucidate Disease

Harnessing the power of big data and machine learning as a digital crystal ball, 2019 Research Scientific Symposium Keynote Speaker Olga Troyanskaya, PhD, showed the audience how her lab is delving into biochemical activity in the vast non-coding regions of the genome to make predictions about genetic variants’ causal connections to rare diseases and complex common disorders. 

A professor at the Lewis-Sigler Institute for Integrative Genomics and the Department of Computer Science at Princeton University, Dr. Troyanskaya wants to find the meaning in the mountain of information genomic databases have compiled in recent years. While each single-nucleotide variant associated with a disease is a stepping stone, she encouraged researchers to reach a greater understanding of specific variants’ function, their effects on gene expression, and how they may influence disease risk and pathophysiology. 

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May 30 2018

Meet Our 2018 CHOP Distinguished Research Trainees

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