Tag Archive: chimeric antigen receptor cell therapy

Jan 30 2019

Borrowing a Weapon From Leukemia’s Arsenal to Develop New Immunotherapy Approaches

More than six years after Emily Whitehead became the first child to receive chimeric antigen receptor (CAR) T-cell therapy, doctors have had remarkable success in turning the immune systems of even more children with acute lymphoblastic leukemia (ALL) into top-notch fighters against the disease. For some patients, however, these superhero T-cells still fail in their mission to find and fight their cancer targets.

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Dec 14 2018

In the News: Gene Therapy EU Approval, Long-Term CAR T-cell Effectiveness, 10 Years of CAR, AHA Conference, CAR T-cell Resistance

The end of the year inevitably arrives with a handful of things to celebrate, from memorable moments to astounding achievements to milestones made. With less than three weeks left in 2018, our list of celebratory moments at Children’s Hospital of Philadelphia Research Institute continues to grow, as this edition of our biweekly research news roundup shows. Read on to learn about two gene therapies pioneered at CHOP and the University of Pennsylvania that recently reached important milestones, a novel discovery from our scientists that could help to improve cancer immunotherapies, the 10-year anniversary of our Center for Autism Research, and more.

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