Feb 15 2013

Searching for the Signs of Autism in Infants

One out of 88 children in the United States has been diagnosed as having an autism spectrum disorder. There is no cure and relatively few treatments that work well for everyone on the autism spectrum. But research, including ground-breaking studies on infants, is making great strides to better understanding autism spectrum disorders.

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Feb 14 2013

Unlocking the Secrets of Mitochondria

mitochondriaA team led by CHOP’s Marni J. Falk, MD, has expanded next-generation gene tools designed to sequence nuclear DNA to analyze a separate source of DNA — that found within mitochondria. Mitochondria are key suppliers of the energy needed for the multiple functions of our cells. Mitochondria contain their own DNA, and play a pivotal role in human health and disease.

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Feb 7 2013

The Cornerstone of Personalized Medicine

personalized medicineThe idea of “personalized” medicine isn’t just about a one-on-one encounter with a doctor, the use of sophisticated mobile applications, or heightened access to healthcare providers, medical records, and services. Personalized medicine also extends into the depths of who each of us are at our essence — to our individual genetic makeup.

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Feb 1 2013

Longer CPR Saves Lives in Children and Adults

CPRTwo recently published studies show that extending cardiopulmonary resuscitation (CPR) longer than previously thought useful saves lives in children and adults. The research teams analyzed the impact of duration of CPR in patients who suffered cardiac arrest while hospitalized.

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Jan 30 2013

Comparing Oral and Intravenous Antibiotics

antibioticsRon Keren, MD, MPH, director of the Center for Pediatric Clinical Effectiveness, was recently awarded nearly two million dollars from the Patient-Centered Outcomes Research Institute (PCORI) to lead a study examining whether oral antibiotics are as effective at treating infection over an extended period as PICC lines.

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Jan 25 2013

CHOP Geneticists to Be Featured on Religion & Ethics Newsweekly

Stay tuned! The work of married CHOP geneticists Ian D. Krantz, MD, and Nancy B. Spinner, PhD, will be featured on PBS’s Religion & Ethics Newsweekly this Friday, January 25. The program will air online ahead of its being shown on television.

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Jan 24 2013

Study Shows Neuroblastoma Evolves Rapidly, Limiting Treatment Targets

neuroblastomaA recent genomic study of neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene mutations — mutations that would suggest new targets for neuroblastoma treatment. Instead, the investigators have refocused on how neuroblastoma tumors evolve in response to medicine and other factors.

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