Feb 6 2018

Does Past Exposure to the Flu Influence Future Immune Responses?

The Finding:

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Feb 1 2018

Join Our Team to Tackle Autism Spectrum Disorder Research

With the entire city soaring from the Eagles Championship win, we can feel even better that our home team also has a heart for research. So take your Eagles fandom to the next level by joining your colleagues, patients, friends, and family on Team CHOP Research in the Eagles Autism Challenge. Not only will you help fund breakthroughs made right here at Children’s Hospital of Philadelphia for the thousands of children and families who are affected by autism, but you will have the opportunity to celebrate on the field with the NFC Champions themselves!

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Jan 30 2018

Richard Aplenc, MD, PhD, MSCE, Sets Course for Clinical Research Operations

A new year brings new beginnings, and in 2018 the Research Institute is welcoming Richard Aplenc, MD, PhD, MSCE, to his new role as assistant vice president and chief clinical research officer. While Dr. Aplenc is new to the Research Institute’s leadership team, his more than two decades of experience at CHOP started with his Pediatric Hematology Oncology fellowship in 1997. Dr. Aplenc joined the faculty in 2002 and is currently a professor of Pediatrics as well as a professor of Epidemiology. In his new role, Dr. Aplenc will set the course for the development and oversight of clinical research operations across Children’s Hospital of Philadelphia. It’s a position that offers big challenges — and even bigger opportunities.

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Jan 26 2018

Quantifying Concussions, Vitamins for Mitochondrial Disease, Autism and Police Encounters, Using Smartphones, Doug Wallace

Smartphones, sports injury, and stories about science: This week in our Children’s Hospital of Philadelphia research roundup, 2018 is in full swing as our investigators made media headlines for their work to advance children’s health. Keep reading to learn about the different ways researchers at CHOP study the benefits and drawbacks of teens’ smartphone use, why research led by concussion experts at our Center for Injury Research and Prevention (CIRP) was featured in a recent philly.com article, and how experts in the Mitochondrial Medicine Frontier Program are weighing in on vitamins and supplements for mitochondrial disease.

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Jan 23 2018

It’s About Exposure: High U.S. Childhood Mortality Rates Due to Car Crashes and Firearm Assaults

Editor’s Note: This post written by Flaura Koplin Winston, MD, PhD, scientific director and founder of the Center for Injury Research and Prevention  (CIRP) at Children’s Hospital of Philadelphia, originally appeared on CIRP's Research in Action blog. View the original blog post here.

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Jan 17 2018

‘Like’ This: PolicyLab Uses Social Media to Support New Moms

From Facebook pages to Twitter feeds, social media has transformed how we communicate and gather news about our world. Seventy-five percent of today’s parents use social media according to a Pew Center Research report, and 79 percent of those parents reported that they learned beneficial information from logging onto their channels. James Guevara, MD, MPH, pediatrician and a founding member of PolicyLab at Children’s Hospital of Philadelphia, has seen the power of these platforms at work while conducting research into mothers with postpartum depression.

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Jan 12 2018

Birth Defects Awareness, Million Dollar Bike Ride Grant, WAO Center of Excellence, Alopecia and Thyroid Screening, New PolicyLab Video

The new year brings brand-new opportunities to advance pediatric research at Children’s Hospital of Philadelphia Research Institute, and if the first two weeks of 2018 are any indication, our investigators are off to a remarkable start. With January marking National Birth Defects Prevention Month, the Center for Fetal Diagnosis and Treatment at CHOP embarked on a campaign to raise awareness for birth defect treatments and research. Meanwhile, our friends at PolicyLab released an exciting video communicating their passionate mission to improve the well-being of children and families. This week, we also cover new pathways to discovery for conditions both rare and common, from hyperinsulinism to alopecia. If (like us), your new year’s resolution is to stay up to date with the latest CHOP research headlines, you’re in the right place!

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Jan 11 2018

Is Autism Associated With Stronger or Weaker Brain Connections?

The Finding:

In a new study that sheds light on a longstanding paradox in autism research, investigators showed how children and teens with autism spectrum disorder (ASD) can have both stronger and weaker brain connections than their typically developing peers. Resting-state functional magnetic resonance imaging (fMRI) revealed that while individuals with ASD have weaker brain connections compared to their peers overall (a measure known as absolute connectivity), they simultaneously exhibited stronger connections within the brain networks implicated in attention and social cognition compared to their other networks (a measure known as relative connectivity). Additionally, the more these brain connections differed from typical development, the more severe the child’s ASD symptoms seemed to be.

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Jan 5 2018

Researchers Take Gaming to a New Level to Help Children With Autism

Each new year comes with anticipation for the latest and greatest in the world of video games to be revealed. Which sequels will surpass their originals? Will beloved characters be reinvented? And we want to know: What brand-new entries are lined up that could offer an amazing experience in field of gaming for health?

The Center for Autism Research (CAR) at Children’s Hospital of Philadelphia has several studies in the works that are looking at the feasibility of using video games and virtual reality to help children improve symptoms of autism. With engaging platforms and cutting-edge graphics, these games are aiming for a “high score” as easy-to-access, affordable, and effective interventions for autism spectrum disorder (ASD). Here’s a quick glance at what is on the horizon:

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Dec 29 2017

Gene Therapy Makes Headlines, Mitochondrial Medicine, Brain Injury Collaboration, Implicit Racial Bias Blog

After a year of huge headlines for children’s health, we’ve finally arrived at our last roundup of Children’s Hospital of Philadelphia research news for 2017. The latest developments cap off a benchmark year of discovery, with new advances in treating childhood blindness, novel initiatives to study traumatic brain injury, and wonderful stories from a variety of media outlets that highlight the efforts and accomplishments of our Mitochondrial Medicine Frontier Program and The Raymond G. Perelman Center for Cellular and Molecular Therapeutics. We think this edition’s collection of news items herald exciting things to come in 2018!

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