Gene therapy researchers at The Children’s Hospital of Philadelphia have produced a bioengineered decoy that by fooling the immune system prevents it from undermining the benefits delivered by a corrective gene.
A team from the Perelman School of Medicine at the University of Pennsylvania recently published a study in Nature Medicine that sheds light on food allergy-associated inflammation.
As part of its mission to find “a cure for all children with cancer,” Alex’s Lemonade Stand Foundation recently announced more than $7 million in new grants to researchers around the country, including four at The Children’s Hospital of Philadelphia. Children’s Hospital investigators Garrett Brodeur, MD, Michael Hogarty, MD, Richard Aplenc, MD, and Robert Schnepp, MD, PhD, all received grants from the organization, for a total of $800,000 in cancer research funding.
On its research advocacy blog Research Means Hope, the Association of American Medical Colleges (AAMC) recently highlighted an innovative immune therapy trial led by researchers from CHOP and Penn that led to the dramatic recovery of one young patient.
Since the completion of the Human Genome Project, there has been a natural surge in biomedical research aimed at gene discovery. Using genome-wide association studies (GWAS), bioinformatics, and other approaches, this process has focused largely on determining what genes are implicated in specific diseases.
Noted microbiologist and Children’s Hospital alumnus Joseph W. St. Geme, III, MD, was recently named CHOP’s Physician-in-Chief and Chair of the Department of Pediatrics at the University of Pennsylvania.
What really goes on in the heads of teenagers? Generations of parents have asked that question, but researchers at the Center for Injury Research and Prevention (CIRP) at CHOP are studying one important aspect of it literally: What happens when a teenager gets a concussion?
The American Society of Clinical Oncology will confer one of its highest awards on Garrett M. Brodeur, MD, who will receive the Pediatric Oncology Award and deliver the Pediatric Oncology Lecture.
As one of the premier pediatric research institutions in the country, The Children’s Hospital of Philadelphia Research Institute has long been committed to education and to training the next generation of pediatric pioneers.
A physician-scientist from The Children’s Hospital of Philadelphia, Elizabeth Goldmuntz, MD, is one of the senior leaders of a research consortium reporting important gene changes that may help explain why children are born with heart defects.