A two-step electronic alert system successfully reduced missed sepsis diagnoses in children by 76 percent. The new pediatric protocol, which incorporates the use of vital signs, risk factors, and a clinician’s judgment, shows promise as a sensitive and specific tool that can help pediatricians working in the emergency department (ED) save lives.
Read on for more exciting headlines from this week, including highlights from our inaugural “Deciphering Beckwith-Wiedemann Syndrome” conference.
It was weekend of firsts on many fronts, as physicians, genetic counselors, nurses, researchers, and families gathered July 21–23 at Children’s Hospital of Philadelphia Research Institute for the inaugural Deciphering Beckwith-Wiedemann syndrome (BWS) conference. BWS is a rare overgrowth disorder involving genetic and epigenetic changes that occur approximately every one in 10,500 births.
I first became interested in neurology when I observed a grade school friend have a seizure. But it wasn’t until after I was chosen to participate in the division of Child Neurology’s annual Neurology High School Scholars Program at CHOP that I decided that I wanted to become a pediatric neurologist.
Researchers from the Children’s Oncology Group (COG) have developed a new standardized dosing method for anticancer drugs in infants to use across all COG clinical trials. This unified method, based on dose banding and organized into tables for different drugs and dose levels, will address the limitations and variability that researchers can encounter in current methods.
CAR T-cell therapy tops this week’s research roundup, with news about the experimental immunotherapy designed to re-engineer a patient’s cells to fight cancer making late-breaking and captivating headlines across the nation.
In the lab of Paula Oliver, PhD, associate professor of Pathology at Children’s Hospital of Philadelphia, a group of researchers led by Awo Layman, PhD; Guoping Deng, PhD; and Claire O’Leary, PhD, studied the influential events that transpire when, as Dr. Layman described it to us, a type of immune cell called a regulatory T cell suffers a “loss of identity.”
As part of the educational program Healthy NewsWorks, young journalists from the Highland Park Healthy Hawk, the East Norriton Bulldog Bulletin, and other student-run newspapers interviewed clinicians and researchers about some of today’s most pressing health topics from gun violence to preventing sports injuries to city health programs for the uninsured.
Every good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.
The Senate-proposed Better Care Reconciliation Act and the House-passed American Health Care Act (AHCA) risk undoing a half century of healthcare standards that were designed to maximize child development and well-being by cutting Medicaid funding and fundamentally changing the program. Yet, the intense discussion on the future of our healthcare system has really only been focused on adults.