Category Archive: Children's Hospital of Philadelphia Research Institute

Oct 16 2018

Steven D. Douglas, MD, Receives 25th Silver Lecture for Pediatric HIV/AIDS Research


With an enterprising career spanning 50 years in basic and clinical immunology and more than 500 publications, Steven D. Douglas, MD, had the honor of presenting the 25th Herman and Gertrude Silver Lecture, in which he reviewed major milestones in the field of pediatric HIV/AIDS and shared his optimism that paradigm shifts and new discoveries are ahead.

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Oct 1 2018

What are Best Practices for Pediatric Nasogastric Tube Placement and Verification?

The findings:

Researchers have published best practice recommendations for nasogastric (NG) tube location placement and verification in pediatric patients. Endorsed by the American Society for Parental and Enteral Nutrition (ASPEN), the recommendations include: provide education; use appropriate NGT placement and securing methods; measure gastric pH; consider a radiograph for any patient in whom there is a concern for correct NGT placement; and improve interpretation and communication about the radiograph.

Why it matters:

Upto this point, no standard for the NG tube insertion procedure existed in the United States. If performed improperly, the common practice has potentially serious or fatal complications, including tubes being placed in the child’s lung or snaking into the brain. In addition, the tube can be inserted into the small intestine rather than the intended target of the stomach.

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Sep 21 2018

In the News: Brain Cancer Gene Therapy, 2019 Eagles Autism Challenge, Mitochondrial DNA in Cardiomyopathy, Kids First DRC, Device Symposium

Fall weather and football season have returned to us here at Children’s Hospital of Philadelphia Research Institute, bringing with them a fresh batch of research headlines. In this edition of our biweekly news roundup, catch up on the latest announcements for the second annual Eagles Autism Challenge, learn about new insights into the role mitochondrial DNA plays in heart disease progression, and stay updated on how CHOP helps to drive medical innovation and entrepreneurship forward in the Philadelphia community and beyond.

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Aug 1 2018

Curious to Confident: Students Bask in Summer Research Experience

Six students from local under-resourced schools eagerly swapped sunglasses for safety goggles and got to work this summer in some of the most sophisticated research laboratories on campus at Children’s Hospital of Philadelphia Research Institute.

The students navigated real-world research settings, practiced lab skills, explored scientific and medical career options, and met mentors who are dedicated to advancing pediatric medicine, as part of the six-week CHOP Research Internship for Scholars and Emerging Scientists (CHOP-RISES) summer internship. The new program is offered by the Office of Academic Training and Outreach Programs (ATOP) at the Research Institute.

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Jul 27 2018

In the News: ROP Screening Tool, Sickle Cell Disease Target, PolicyLab Keynote, 2018 St. Baldrick’s Grants

It’s still a month before teachers and students are officially back to school, but here at Children’s Hospital of Philadelphia Research Institute, you can learn something new every day. In this edition of our biweekly news roundup, discover the latest findings from our ophthalmologists on how clinicians should choose to screen premature babies for a potentially blinding eye disorder, find out how CRISPR-based technology allowed scientists to reveal insights into sickle cell disease, and prepare for an educational and exciting speech from the recently announced keynote speaker at PolicyLab’s upcoming 10th Anniversary Forum

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Feb 28 2018

Better Biobanking a Best Bet for Rare Disease Research

Editor’s Note: Families facing a rare disease diagnosis often do not know where to turn first in their search for the most advanced treatments and potentially a cure for their children. Only 5 percent of rare diseases have a treatment approved by the Food and Drug Administration, according to the National Organization for Rare Disorders. This is due in part to the lack of high quality biospecimens for research.

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Jan 30 2018

Richard Aplenc, MD, PhD, MSCE, Sets Course for Clinical Research Operations

A new year brings new beginnings, and in 2018 the Research Institute is welcoming Richard Aplenc, MD, PhD, MSCE, to his new role as assistant vice president and chief clinical research officer. While Dr. Aplenc is new to the Research Institute’s leadership team, his more than two decades of experience at CHOP started with his Pediatric Hematology Oncology fellowship in 1997. Dr. Aplenc joined the faculty in 2002 and is currently a professor of Pediatrics as well as a professor of Epidemiology. In his new role, Dr. Aplenc will set the course for the development and oversight of clinical research operations across Children’s Hospital of Philadelphia. It’s a position that offers big challenges — and even bigger opportunities.

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Nov 22 2017

A Heartfelt Thank You

Our days and weeks are packed – sometimes to the point of overflowing – with projects, meetings, and the regular day-to-day work that propels our discoveries and supports our investigators and their teams.

In the midst of being busy today and planning for tomorrow, it’s important for me to take a moment to express my gratitude to everyone for what they do to support the CHOP Research Institute.

While funding is certainly a critical factor in our flourishing research program, it has little significance without you – our innovative investigators and research teams, our dedicated support staff, our generous donors, and our inspiring patients and families. I am thankful for each and every one of you for your tireless support. Regardless of how you support the Research Institute – through your work, generosity, advocacy, and goodwill – please know that we could not accomplish what we do without you.

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Oct 9 2015

Research Institute’s Bryan Wolf, MD, PhD, New to Pennsylvania Bio Board

The Children’s Hospital of Philadelphia’s Research Institute is among 2,300 life sciences establishments that call Pennsylvania home. As a newly appointed member of Pennsylvania Bio’s Board of Directors, Bryan Wolf, MD, PhD,

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