Category Archive: Children's Hospital of Philadelphia Research Institute

Jun 14 2019

In the News: Eagles Autism Challenge, ASCO Young Investigator, Innovation in Collaboration, Trauma and Development, Post-Injury Mental Health, AWHONN Award

We’re sailing into the middle of June with yet another set of exciting headlines, from the fundraising results of this the 2019 Eagles Autism Challenge, to two new awards that support researchers in our Cancer Center at Children’s Hospital of Philadelphia, to novel insights into mental health after a serious injury, and to discoveries about the impact of trauma and poverty on brain development. Read on for the latest CHOP research news!

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Jun 10 2019

Researchers Study How To Enhance Self-management of Survivors of Childhood Cancer

by lavigne

Adolescents and young adults with a history of cancer may seem prepared to handle anything that comes their way and want to move on with their lives. Unfortunately, too often what gets left behind is cancer survivors’ commitment to engaging in long-term follow-up care. As their recommended annual appointment rolls around, they may not be motivated to take it seriously when they’re asymptomatic and feeling fine. 

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Jun 7 2019

Fusing Computational Genomics and Functional Genomics To Elucidate Disease

Harnessing the power of big data and machine learning as a digital crystal ball, 2019 Research Scientific Symposium Keynote Speaker Olga Troyanskaya, PhD, showed the audience how her lab is delving into biochemical activity in the vast non-coding regions of the genome to make predictions about genetic variants’ causal connections to rare diseases and complex common disorders. 

A professor at the Lewis-Sigler Institute for Integrative Genomics and the Department of Computer Science at Princeton University, Dr. Troyanskaya wants to find the meaning in the mountain of information genomic databases have compiled in recent years. While each single-nucleotide variant associated with a disease is a stepping stone, she encouraged researchers to reach a greater understanding of specific variants’ function, their effects on gene expression, and how they may influence disease risk and pathophysiology. 

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Jun 5 2019

Consortium Guides Innovation in Pediatric Medical Devices

By Barbara Drosey

You’re a renowned pediatric plastic surgeon with a novel idea: a noninvasive solution to correct infant ear deformities that can save a child from potential self-esteem and functional issues. After creating a simple prototype of a molding device, you know you’re on the right track, but what are the next steps to ensure this solution reaches the right patients?

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May 31 2019

In the News: Repeat Concussions, Epilepsy Gene, Skin Patch for EoE, Food Insecurity Screening, New Director of Academic General Pediatrics Fellowship

By Nancy McCann

Happy unofficial start to summer 2019! If you find yourself looking for something good to read on the beach, in the backyard, or floating on a boat, here you go. Discover which Children’s Hospital of Philadelphia docs and researchers have been in the news recently. We’re covering the risk of repeat concussions, a best method to screen for food insecurity, and a newly discovered causative gene for severe childhood epilepsy.

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May 29 2019

2019 Scientific Symposium Sparks Discussions on Big Data

By Jillian Rose Lim, Barbara Drosey, Sharlene George, and Nancy McCann

Researchers exchanged big ideas about big data at the 2019 Scientific Symposium, an event that brought together the bright minds of our Children’s Hospital of Philadelphia research community. A lineup of thought-provoking speakers from CHOP and the University of Pennsylvania shared presentations corresponding with the symposium’s themes, “Big Data” and “Today’s Discoveries and Tomorrow’s Possibilities.” 

“The goal [of this symposium] is to highlight the tremendous advances by CHOP investigators in the booming fields of computational biology, data science, and genomics,” said Yi Xing, PhD, chair of the event and director of the Center for Computational and Genomic Medicine at CHOP. 

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May 22 2019

Babette Zemel, PhD, Recognized at 2019 Scientific Symposium for Mentoring

By Jillian Rose Lim

The 2019 Scientific Symposium, held today, May 22, celebrates the Research Institute’s remarkable scientific community: a diverse group of thought leaders, innovators, experts, and early career scientists committed to advancing children’s health. Within this community, faculty mentors play an important role in shaping our culture of research excellence by sharing their wisdom and guidance. The Children’s Hospital of Philadelphia Faculty Mentor Award, which was presented at this morning’s symposium, is a special honor given to faculty investigators whose mentoring has helped their colleagues become the next generation of brilliant researchers at CHOP.   

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May 17 2019

In the News: Early Investigator Award, Microbiome and Depression, INSAR 2019, Families’ Internet Searches, Telehealth Grant, and Pediatric Medical Devices

In this week’s news roundup, a Children's Hospital of Philadelphia researcher is recognized for her work to improve clinical effectiveness for children with endocrine-related diseases, and Center for Autism scientists present findings to the international autism research community. 

Other highlights include an investigation of the effects of the microbiome on the brain that could lead to novel treatments for psychiatric conditions, a look into Google searches as a mechanism to offer more tailored support and education to families with children newly diagnosed with cancer, and a funding boost for telehealth research. In addition, the CHOP-based Pennsylvania Pediatric Medical Device Consortium announced its latest seed grants to support the creation and development of medical devices designed for children. 

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May 9 2019

‘Superheroes’ Receive 2019 Clinical Research Coordinator RE@CH Award

By Nancy McCann 

It was no easy feat for two “superhero” clinical research coordinators (CRCs) to rise to the top of nominees at the 6th annual CRC Research Excellence @ Children’s Hospital (RE@CH) Award ceremony because they were in the company of extraordinaires. 

Congratulations go out to the 2019 CRC RE@CH Award winners Katherine Kellom, a qualitative methods program manager at CHOP’s PolicyLab, and Lindsay Waqar, MPH, CCRC, a clinical research coordinator in the Division of Rheumatology. Their nominating principal investigators were Meredith Matone, DrPH, MHS, and Pamela Weiss, MD, MSCE, respectively.  

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May 8 2019

Exploring Exosome-Mediated Stem Cell Engraftment for Hemoglobinopathies

By Barbara Drosey

Intent on pursuing a career in fetal surgery since age 11, Meghana V. Kashyap, MD, a general surgery resident at the University of Nebraska Medical Center, reached out to five prominent fetal surgery centers to determine where her two years of dedicated research, allowed by her training program, would best be spent.

“Every program I interviewed with had done their training under Dr. (Alan) Flake and his colleagues here at Children’s Hospital of Philadelphia,” Dr. Kashyap said. “I thought, why not train at the institution that produced these other surgeon-scientists?”

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