Breakthroughs in basic science build the foundation for clinical research and our treatment of children’s health. Many basic scientists, however, find themselves wanting to play a more active role in connecting their lab discoveries from the bench to the bedside. The Office of Postdoctoral Affairs at Children’s Hospital of Philadelphia held a Q&A panel, “How to Break Into Translational Research As a Basic Scientist,” in October as part of their week-long, biannual Translational Research Workshop.
Category Archive: Perelman School of Medicine
Around seven years ago during a well visit at Children’s Hospital of Philadelphia, a 12-year-old boy told Saba Khan, MD, an attending physician at CHOP, that there was one problem she could not fix. Intrigued, Dr. Khan asked him to explain further. At first hesitant, the young man finally explained what he meant. He had a pain in his belly that never went away, and he knew exactly what that pain was: Hunger. “I’m always hungry,” he said to Dr. Khan.
Dr. Khan was floored. At the time, she was unfamiliar about how to address the issue of food insecurity because she had not yet encountered it in primary care practice.
September marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research. Oncology investigators at CHOP also got a big boost in research funding from Hyundai’s nonprofit organization, Hope on Wheels. And that’s only the beginning: Since September marks the return of the football season, we’re thrilled to share the latest headlines on how the National Football League (NFL) is helping to drive concussion research.
It was a pivotal moment that has turned into a new era for cancer immunotherapy. On April 17, 2012, Children’s Hospital of Philadelphia researchers for the first time treated a pediatric patient with a cellular therapy that used her own reprogrammed immune cells, called T cells, to attack her aggressive form of blood cancer.
Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.
Don’t let those crisp, white lab coats fool you. While researchers share the ultimate goal of reaching new findings that can advance the best possible medical care, they aren’t all the same.
Read on for more exciting headlines from this week, including highlights from our inaugural “Deciphering Beckwith-Wiedemann Syndrome” conference.
It was weekend of firsts on many fronts, as physicians, genetic counselors, nurses, researchers, and families gathered July 21–23 at Children’s Hospital of Philadelphia Research Institute for the inaugural Deciphering Beckwith-Wiedemann syndrome (BWS) conference. BWS is a rare overgrowth disorder involving genetic and epigenetic changes that occur approximately every one in 10,500 births.
Every good researcher needs a sturdy set of tools: Whether it’s a new technology that drives efficiency, the financial support that accompanies an award, or simple advice from a research mentor, all of these resources make collective breakthroughs possible.
The Violence Prevention Initiative (VPI) at Children’s Hospital of Philadelphia is a standout example of how our research is taking hold in communities, and now the entire country knows more about it after a live broadcast by “Good Morning America” at our Karabots Pediatric Care Center featuring an interview with Madeline Bell, president and chief executive officer of CHOP.