Category Archive: Children's Hospital of Philadelphia

Nov 4 2015

Tiny Mitochondria Play Outsized Role in Human Evolution and Disease

Cells under microscopeMitochondria are not only the power plants of our cells; these tiny structures also play a central role in our physiology. Furthermore, by enabling flexible physiological responses to new environments, mitochondria have helped humans and other mammals to adapt and evolve throughout the history of life on earth.

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Nov 3 2015

Drug Trial Shows “Profound” Success Treating Rare Blood Disorders

rare_blood_disorderWhen the immune system inappropriately destroys blood cells, in a relatively rare group of diseases called autoimmune cytopenias, children may suffer for years with anemia, uncontrolled bleeding, and vulnerability to infections, while their parents struggle to find a diagnosis.

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Oct 28 2015

More Effective Strategies Needed to Prevent Abusive Head Trauma

AHTWhen parents feel exhausted, stressed, and frustrated by their inconsolable infant, they may reach a flash point and injure their baby. Devastating head injuries can result from forceful shaking and blunt impact.

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Oct 8 2015

Missing Well Visits Results in Preventive Care Gaps for Preterm Infants

Newborns’ first big journeys into the world often are to well-baby exams at pediatricians offices. These checkups usually are scheduled within the first days or weeks after discharge from the hospital, followed by exams every few months during their first year of life.

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Oct 6 2015

Focus on Vision and Balance Deficits Following Youth Concussion

Recognizing a concussion oftentimes is not crystal clear for clinicians. A young patient with a head injury may report experiencing common concussion symptoms, and yet results from a standard physical exam seem normal.

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Sep 29 2015

MOMS Study Suggests Candidates, Timing for Fetal Spina Bifida Surgery

Fetal spina bifida surgery to repair myelomeningocele is a remarkable and intricate procedure performed before birth. If untreated, spinal cord damage from amniotic fluid exposure is progressive during gestation.

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Sep 23 2015

New Research Consortium Aims to Identify Drugs for Pediatric Cancers

The Children’s Hospital of Philadelphia and four other high-profile oncology research programs plus a coordinating center joined the new Pediatric Preclinical Testing Consortium (PPTC) launched by the National Cancer Institute (NCI) to help researchers identify drug candidates for pediatric clinical trials.

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Sep 22 2015

Vs. Cancer and CBTTC a Winning Team for Childhood Brain Tumor Research

Young Boy Playing BaseballFrom pitchers and catchers to fast base runners and big hitters, baseball rosters need a diverse range of skills, but to achieve victory, individual players need to work together. Such dedication to collaboration also is a winning game plan when patients, clinicians, researchers, and donors team up to accelerate the study of childhood brain tumors.

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Sep 17 2015

Teaching the Immune System to Have Long-term Memory for Leukemia

A CHOP cancer patient adding her colorful symbols of hope to a white car that is covered with children’s handprints from all over the country.Your immune system is designed to protect against foreign invaders such as infections, but you may not realize that it also destroys abnormal cells that your body produces.

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