Editor’s note: The Children’s Hospital of Philadelphia Research Institute Summer Scholars Program (CRISSP) is a competitive and dynamic internship that provides undergraduate students with hands-on experience in academic research, exposure to various facets of a career in pediatric research and/or medicine, and direct mentoring by CHOP faculty. In this guest blog, Cindy Hong, a rising third-year student at University of the Sciences in Philadelphia, gives a glimpse into her experience as a 2019 CRISSP scholar embarking on the immersive 10-week internship — from learning new skills in biomedical and health informatics in the lab of Laura Almasy, PhD, to making new friends, to determining if research is a career she wants to pursue.
Monthly Archive: July 2019
Start new collaborations. Find valuable data. Create cohorts that can seed new research endeavors. These are some of the key drivers for Arcus, an internal strategic program designed for researchers to more intuitively navigate clinical and research data produced by Children’s Hospital of Philadelphia and the Research Institute. Essentially, that means making the promising wealth of data in Arcus discoverable.
In this Cornerstone post, meet Spencer Lamm, MLIS, supervisor of Library Science within the Department of Biomedical and Health Informatics (DBHi), who is adopting standards and practices for managing large volumes of data at places like NASA to make the new Arcus Archives a source of reliable, reproducible data for CHOP researchers long-term.
The Fourth of July fireworks may be over, but sparks are still sizzling (along with the weather) here at the Research Institute as we celebrate our researchers’ published work. Take a look at who’s been in the press lately. This week we’re covering the decision factors behind allowing children to ride alone in self-driving cars, commentary on improving perinatal care in the United States, and why private sector working families are turning to Medicaid and CHIP for health coverage.
By Nancy McCann
Editor’s note: We’ve started a new occasional blog series! Do you ever wonder what our super-docs and super-staff do on the weekends, during their downtime? Well, our Research Communications team did, and we created “Off Campus” to discover what our amazing Research Institute employees do for fun, recreation, and the good of their communities. Get a glimpse into their lives once they take off their capes … umm, we mean lab coats and business shoes. And if you know someone in your department or lab with a fascinating hobby or interest, we’d like to hear about it!
By Barb Drosey, Jillian Rose Lim, Nancy McCann, and Sharlene George
Editor’s Note: Where Discovery Leads is a multimedia storytelling project that delves into key research themes at CHOP Research Institute. This is part one of a two-part series that focuses on the suite of scientific studies aimed at better understanding the neuropathogenesis of HIV infection on cognitive and intellectual development. See part two of this series.
By Jillian Rose Lim
Editor’s Note: Where Discovery Leads is a multimedia storytelling project that delves into key research themes at CHOP Research Institute. This is part two of a two-part series that focuses on the suite of scientific studies aimed at better understanding the neuropathogenesis of HIV infection on cognitive and intellectual development and to improve support services for affected children and adolescents. See part one of this series.
Youth living with HIV in limited-resource settings face unique challenges when it comes to mental health. In Botswana, a country with one of the highest HIV prevalence rates in the world, few accessible places exist for children and adolescents to receive mental healthcare.
A study team at Children’s Hospital of Philadelphia discovered a gain-of-function mutation in the ARAF gene causing a life-threatening rare disease known as central conducting lymphatic anomaly that disrupts circulation of lymphatic fluid. They also identified an existing drug that acts on biological pathways affected by ARAF. The experimental treatment had dramatic results for a young boy with the disease who had worsening respiratory and swelling problems. The drug blocked the signals causing the dysregulated growth and abnormal lymphatic flow, prompting his lymphatic channels to reshape themselves into more normal anatomy and function.