May 2019

Monthly Archive: May 2019

May 22 2019

Babette Zemel, PhD, Recognized at 2019 Scientific Symposium for Mentoring

By Jillian Rose Lim

The 2019 Scientific Symposium, held today, May 22, celebrates the Research Institute’s remarkable scientific community: a diverse group of thought leaders, innovators, experts, and early career scientists committed to advancing children’s health. Within this community, faculty mentors play an important role in shaping our culture of research excellence by sharing their wisdom and guidance. The Children’s Hospital of Philadelphia Faculty Mentor Award, which was presented at this morning’s symposium, is a special honor given to faculty investigators whose mentoring has helped their colleagues become the next generation of brilliant researchers at CHOP.   

Read the rest of this entry >>

May 20 2019

Do Mothers’ and Babies’ Genes Influence Birth Weight?

The Findings:

An international research team conducted a large study and learned that genetic factors from both mothers and babies interact to influence birth weight. The researchers identified 190 genetic signals from variants affecting birth weight, of which 129 signals were new discoveries. The researchers also demonstrated that some of the mother’s genes were not inherited by the baby, but they did influence the baby’s uterine environment during pregnancy.

Read the rest of this entry >>

May 17 2019

In the News: Early Investigator Award, Microbiome and Depression, INSAR 2019, Families’ Internet Searches, Telehealth Grant, and Pediatric Medical Devices

In this week’s news roundup, a Children's Hospital of Philadelphia researcher is recognized for her work to improve clinical effectiveness for children with endocrine-related diseases, and Center for Autism scientists present findings to the international autism research community. 

Other highlights include an investigation of the effects of the microbiome on the brain that could lead to novel treatments for psychiatric conditions, a look into Google searches as a mechanism to offer more tailored support and education to families with children newly diagnosed with cancer, and a funding boost for telehealth research. In addition, the CHOP-based Pennsylvania Pediatric Medical Device Consortium announced its latest seed grants to support the creation and development of medical devices designed for children. 

Read the rest of this entry >>

May 14 2019

CHOP Awarded Inaugural Eagles Autism Challenge Grants

The soggy start to last year’s inaugural Eagles Autism Challenge didn’t keep more than 3,000 cyclists, runners, and walkers from joining the cause to raise funds for innovative research and programs to learn more about autism spectrum disorder (ASD). If participants minded the rain, you couldn’t tell from the smiling faces peeking from under hoods and hats. 

The Challenge raised $2.5 million to address the complexities of autism through collaborative research among founding beneficiary partners Children’s Hospital of Philadelphia, Drexel University, and Thomas Jefferson University and Jefferson Health. These organizations aim to share their discoveries to advance autism research in Philadelphia and around the world. 

Read the rest of this entry >>

May 12 2019

Making Time for Science: Meet Jaxson and Megan, Research Hero and Super Mom

by Nancy McCann

Editor’s Note: This occasional blog series features stories of CHOP research heroes who have participated in clinical research studies. Without the generosity and dedication of families, patients, and members of the public who take the time to be a part of research, many trials would not succeed.

The alarm rings annoyingly loud at 6:30 a.m. Megan Payne knows she must rise with that blaring beep, or else the day goes haywire. With five young children to monitor, mornings are a blur of making breakfasts, packing lunches, brushing hair, and searching for lost homework before four kids leave the house at different times to board different buses to attend different schools. Only her youngest, 3-year-old Jaxson, remains behind. Oh, and Megan works three jobs and is a college student studying Environmental Science. Whew.

Read the rest of this entry >>

May 10 2019

Four CHOP Docs Receive 2019 Perelman School of Medicine Teaching Awards

By Nancy McCann 

It’s Teacher Appreciation Week, and we’re taking our big thinking-caps off to four teachers of excellence honored by the Perelman School of Medicine at the University of Pennsylvania. A total of 18 professors with a penchant for pedagogy were selected for the 2019 teaching awards, and four of the honorees share their talents with Children’s Hospital of Philadelphia and its Research Institute:

Read the rest of this entry >>

May 9 2019

‘Superheroes’ Receive 2019 Clinical Research Coordinator RE@CH Award

By Nancy McCann 

It was no easy feat for two “superhero” clinical research coordinators (CRCs) to rise to the top of nominees at the 6th annual CRC Research Excellence @ Children’s Hospital (RE@CH) Award ceremony because they were in the company of extraordinaires. 

Congratulations go out to the 2019 CRC RE@CH Award winners Katherine Kellom, a qualitative methods program manager at CHOP’s PolicyLab, and Lindsay Waqar, MPH, CCRC, a clinical research coordinator in the Division of Rheumatology. Their nominating principal investigators were Meredith Matone, DrPH, MHS, and Pamela Weiss, MD, MSCE, respectively.  

Read the rest of this entry >>

May 8 2019

Exploring Exosome-Mediated Stem Cell Engraftment for Hemoglobinopathies

By Barbara Drosey

Intent on pursuing a career in fetal surgery since age 11, Meghana V. Kashyap, MD, a general surgery resident at the University of Nebraska Medical Center, reached out to five prominent fetal surgery centers to determine where her two years of dedicated research, allowed by her training program, would best be spent.

“Every program I interviewed with had done their training under Dr. (Alan) Flake and his colleagues here at Children’s Hospital of Philadelphia,” Dr. Kashyap said. “I thought, why not train at the institution that produced these other surgeon-scientists?”

Read the rest of this entry >>

May 3 2019

Where Discovery Leads: Capturing the Complexity of Autism

By Jillian Rose Lim, Nancy McCann, Barbara Drosey, and Sharlene George

Editor’s Note: Where Discovery Leads is a multimedia storytelling project that delves into key research themes at CHOP Research Institute. This is part one of a three-part series that focuses on novel diagnostic tools and approaches being developed under the leadership of the Center for Autism Research at CHOP. See part 2 and part 3 of the series.

Read the rest of this entry >>

May 3 2019

Where Discovery Leads: New Phone App for Name Recognition to Aid Autism Screening

By Nancy McCann

Editor’s Note: Where Discovery Leads is a multimedia storytelling project that delves into key research themes at CHOP Research Institute. This is part two of a three-part series that focuses on novel diagnostic tools and approaches being developed under the leadership of the Center for Autism Research at CHOP. See part 1 and part 3 of this series.

A child’s diminished response to hearing his or her name has long been recognized as a red flag for autism spectrum disorder (ASD), and now researchers have developed a phone app to quantitatively measure this behavior as a way to help screen for this complex neurodevelopmental diagnosis.

Read the rest of this entry >>