July 2018

Monthly Archive: July 2018

Jul 27 2018

In the News: ROP Screening Tool, Sickle Cell Disease Target, PolicyLab Keynote, 2018 St. Baldrick’s Grants

It’s still a month before teachers and students are officially back to school, but here at Children’s Hospital of Philadelphia Research Institute, you can learn something new every day. In this edition of our biweekly news roundup, discover the latest findings from our ophthalmologists on how clinicians should choose to screen premature babies for a potentially blinding eye disorder, find out how CRISPR-based technology allowed scientists to reveal insights into sickle cell disease, and prepare for an educational and exciting speech from the recently announced keynote speaker at PolicyLab’s upcoming 10th Anniversary Forum

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Jul 20 2018

Charting a Course for Children With Kidney Disease

Susan Furth, MD, PhD

Children are not just little adults”: It’s a phrase heard often in pediatric medicine, whether you’re a parent, doctor, or researcher. With their dynamically developing bodies, unique psychology and biolochronic kidney disease (CKD) is just one example of a condition whose causes, consequences, and outcomes differ distinctly from adults. And at Children’s Hospital of Philadelphia, clinician-researchers in our Division of Nephrology are constantly learning more about the important differences between pediatric and adult CKD.,>

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Jul 18 2018

CHOP’s Inflammatory Bowel Disease Symposium Attracts Leading Experts

With the rate of inflammatory bowel disease (IBD) continuing to rise, especially in the hard-the-treat population of young children, the timing couldn’t be better for the Children’s Hospital of Philadelphia’s “Personalized IBD and VEO-IBD: Genomics, Microbiome, Biologics, and Beyond” symposium.

This symposium was of particular interest because of the unique combination of the latest research developments with the most up to date advances in clinical care for very-early-onset inflammatory bowel disease (VEO-IBD) and pediatric IBD, said course Co-director Judith R. Kelsen, MD, director of CHOP’s Very Early Onset Inflammatory Bowel Disease Clinic.

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Jul 16 2018

Team Huddles and Positive Feedback Enhance Research Participant Recruitment

Editor’s Note: Our guest blogger, Lindsay Waqar, MPH, CCRC, is the lead clinical research coordinator for the Division of Rheumatology at Children’s Hospital of Philadelphia. In this guest blog, she describes a collaborative quality improvement project presented at the Eighth Annual CHOP Quality and Safety Day between her research team and clinical fellows’ team to improve communication and research recruitment across the division.

What happens when researchers and clinicians team up to improve the identification of eligible research patients newly diagnosed with a chronic condition? Areas of change are discussed, low effort/high impact interventions are implemented, and research recruitment rates improve. This was the goal of the Division of Rheumatology’s fellow quality improvement project for FY18.

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Jul 13 2018

In the News: ALSF Epidemiology Grant, Button Battery Guidelines, PolicyLab Anniversary, EHR-Phenolyzer, Distracted Driving

In this week’s roundup of headlines at Children’s Hospital of Philadelphia, our research takes a leap into real-world applications. Learn how a study from ear, nose, and throat experts at CHOP helped to inform new button battery injury guidelines from the National Poison Center, why a software tool that mines through genomics data can improve genetic diagnoses, and what PolicyLab plans to achieve at their upcoming 10thanniversary forum, “Charting New Frontiers in Children’s Health Policy and Practice.” Don’t miss a chance to discover the latest in research news!

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Jul 10 2018

Do Oral Antibiotics Play a Role in Kidney Stone Prevalence Increase in Youth?

The Findings: Children and adults treated with five classes of oral antibiotics have a significantly higher risk of developing kidney stones. The five classes include oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins. Patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones. For broad-spectrum penicillins, the increased risk was 27 percent higher. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics. The risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

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Jul 6 2018

Eaise Family Rallies for Brain Tumor Research

Debbie Eaise remembers the day her 18-year-old son, Kevin, walked onto the University of Pennsylvania campus where he is set to play for the Penn Quakers baseball team this fall. From Meiklejohn Stadium, Penn’s home field, you can pitch a baseball and reach Children’s Hospital of Philadelphia, said Debbie — a proximity so palpable that she could see the change in her son’s face and sense his comfort level at ease while he toured his future school.

As her husband, Kevin Sr., and others have noted, Kevin has come full circle. It was right there on the Penn-CHOP campus, after all, with its skyline of medical buildings, that Kevin and his family’s life changed inextricably, ushering in what Debbie describes as their “new normal.”

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