May 2018

Monthly Archive: May 2018

May 25 2018

CHOP Researchers Launch Website to Get Parents Talking About Teen Health

A new website developed by a team at Children’s Hospital of Philadelphia is giving parents the opportunity to engage in a dynamic conversation about adolescent sexual health, and not just with teens, but with fellow parents and experts in adolescent medicine across the online community, too. Parents Are T.A.L.K.I.N.G (PAT) which stands for “Teaching A Lifetime of Knowledge About Sexuality in the Net Generation”, was developed to improve adolescent reproductive health by helping parental caregivers learn new skills and information in a convenient and reliable way.

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May 24 2018

Collaborative Discovery Supports Next Wave of Pediatric Brain Tumor Innovation

Editor’s Note: Childhood brain tumors remain some of the most difficult to treat cancers, especially because of current therapies’ long-term side effects for the survivors. In honor of Brain Tumor Awareness Month, Adam Resnick, PhD, director of the Center for Data-Driven Discovery in Biomedicine (D3b) at Children’s Hospital of Philadelphia, is our guest blogger. He brings us up to date on how the CHOP-led consortia, working with patients, families, and partnering institutions, has witnessed first-in-kind initiatives and innovative clinical trials aimed at personalized, precision-based approaches for brain tumors that are redefining the scientific landscape of research and therapeutic translation.

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May 22 2018

Physician-Scientist Jason Van Batavia, MD, Accepts Prestigious Urology Prize

Leading-edge neuroscience techniques are facilitating Children’s Hospital of Philadelphia researchers’ better understanding of how the brain controls bladder function, and their novel insights have earned them special recognition from the neurourology community.

Jason Van Batavia, MD, a urologist and physician-scientist in the Division of Urology at CHOP, is the grand prize winner in the 2018 Diokno-Lapides Essay Contest. His manuscript described a research project focused on optogenetic stimulation of specific neurons in a section of the brainstem called Barrington’s nucleus, which scientists think is an important “command center” for controlling voiding (urination).

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May 18 2018

Pediheart Podcast, EPA Asthma Award, Walk for Hope, Antibiotics and Kidney Stones, Gilyena Approval, Autism Challenge

In our latest roundup of Children’s Hospital of Philadelphia research headlines, learn how our investigators took their discoveries from the bench to the bedside (and beyond), gaining local and national recognition for their hard-earned advances in interventional cardiology practice, asthma management, multiple sclerosis (MS), and more. On top of that, we give you updates on April’s successful Walk for Hope and share our excitement for this Saturday’s Eagles Autism Challenge — two fun-filled family events that illustrate just how much scientific breakthroughs rely on both the community and our scientists.

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May 16 2018

Celebrating the Research Legacies of Drs. Barbara Schmidt and Haresh Kirpalani

neonatology

The Division of Neonatology at Children’s Hospital of Philadelphia celebrated the remarkable research careers and retirement of two pioneers in neonatal research and medicine, Barbara Schmidt, MD, and Haresh Kirpalani, MD, with a clinical research symposium May 9 and 10. Held at the Union League of Philadelphia, the event brought together the world’s leading experts in neonatal research and evidence-based medicine, many of whom have worked closely with Drs. Schmidt and Kirpalani as trainees, co-authors, and colleagues in the last few decades.

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May 11 2018

Clinical Research Coordinators Get Crowns and Congratulations

Clinical research coordinators are the heart and soul of our research breakthroughs, as many of our investigators and staff at Children’s Hospital of Philadelphia know. Whether they’re ensuring that a study falls within regulatory protocols, explaining the science behind a health condition to a family, or simply spending time with patient participants to put them at ease, coordinators bridge the gap between an idea and its execution, as well as between scientists and the patients whose outcomes they hope to improve.

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May 8 2018

Mapping Out Journeys of Changing Hopes for Seriously Ill Children

Editor’s Note: In his career as a social psychologist, Douglas Hill, PhD, focuses on understanding how parents, children, and healthcare providers think about and cope with stressful health situations. For the past six years, Dr. Hill has worked with an interdisciplinary team in the lab of Chris Feudtner, MD, PhD, MPH, on research topics including hopeful thinking among parents of children with serious illness, regoaling, good parent beliefs, coping skill interventions for parents, barriers to initiation of palliative care among pediatric oncologists, the impact of pediatric illness on families, and identifying pediatric patients who are unable to communicate.

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May 4 2018

Pediatric Academic Societies Meeting Packed With Discovery and Discussion

For many of our researchers, the annual Pediatric Academic Societies (PAS) Meeting is more than just another conference or convention: It’s an exciting and educational event filled with discovery and discussion about the myriad ways we can improve children’s health. This year, experts from Children’s Hospital of Philadelphia will convene in Toronto from May 5 to 8 for four days of networking, presentations, poster sessions, and awards. They’ll represent a range of pediatric fields — from behavioral health to bone health, injury research to emergency medicine, neonatology to autism spectrum disorder (ASD), and almost everything in between.

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May 2 2018

Sabin Institute Honors Paul Offit, MD, Vaccine Champion

Paul Offit, MD, director of Children’s Hospital of Philadelphia’s Vaccine Education Center (VEC) and Maurice R. Hilleman Chair of Vaccinology at Penn, added “gold medalist” to his vibrant list of honors and accolades, as he stepped up to receive the 2018 Albert B. Sabin Gold Medal from the Sabin Vaccine Institute last week in Washington D.C. The award complements Dr. Offit’s impactful, decades-long career as a researcher, author, professor, and strident spokesperson for accurate science, not to mention a champion for vaccine advocacy who has reached a range of audiences from the scientific to the mainstream, and from adults to children.

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May 1 2018

Does an Impaired Biological Pathway Help Explain Heart Problems in Huntington’s Disease?

The Findings:

Researchers gained new insights into the heart problems that are the second leading cause of death in patients with Huntington’s disease (HD). An incurable, inherited disease with progressive loss of brain cells and motor function, HD occurs when a defective gene produces repeated copies of a protein called huntingtin, or HTT. The mutant HTT (mHTT) protein disrupts multiple fundamental cellular processes along the mTORC1 pathway that promotes cell growth and metabolism. The study team described how decreased mTORC1 activity contributed to the development of heart disease with stress in mouse models of HD. By restoring cardiac mTORC1 activity, the researchers improved the animals’ heart function and survival over the course of the study.

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