December 2012

Monthly Archive: December 2012

Dec 28 2012

Gene Therapy Shows Promise For Helping Children With Canavan Disease

Canavan Canavan disease is a rare inherited neurological disorder with devastating effect. The lack of a specific enzyme, called aspartoacylase, causes the body’s central nervous system to break down. The disease is usually fatal before a child reaches the teenage years.

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Dec 27 2012

CHOP Study Finds Need for Concussion Management Tools

concussion A study of physicians’ knowledge of and attitudes toward concussion management practices points to the need for improved concussion-specific training and infrastructure to support optimal patient care. The findings, recently published online in Pediatrics, led The Children’s Hospital of Philadelphia (CHOP) to create a new “medical home” model for managing adolescent and pediatric concussion.

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Dec 21 2012

CHOP Researchers’ DNA Work Highlighted in Time

Time_cover_12.24.12After a decade of work and at an expense of nearly $3 billion, the sequencing of the human genome was completed in 2003. Advances since then have made individual sequencing much more widely available — an individual’s genome can now be sequenced in months, for a few thousand dollars.

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Dec 18 2012

Putting the Pieces Back Together: The Aftermath of the Newtown Tragedy

Sandy_Hook_aftermathThe Center for Autism Research (CAR) at The Children’s Hospital of Philadelphia works to make rapid progress in understanding the underlying causes of autism. CAR’s mission is based on the principle that effective treatments for autism spectrum disorders, or ASD, will only emerge with increased understanding of the causes.

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Dec 17 2012

Exploring the Relationship Between Autism and Anxiety

anxiety in autismAutism spectrum disorders (ASD) - a family of developmental disorders associated with complex social challenges - can be scary, and not just because autism’s causes remain largely unknown, or because effective treatments are elusive. Autism is also scary because its prevalence seems to be on the rise.

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Dec 14 2012

New Study Shows Home Visiting Program May Be Struggling to Reduce Childhood Injuries

PolicyLab_Childhood_injuriesOne of the nation’s largest programs providing home visitation support for at-risk mothers and children may not be as successful in reducing early childhood injuries as it was in earlier evaluations, according to new research findings from the Children's Hospital...

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Dec 12 2012

A Year in Review

The holiday season is once again upon us! While it’s a time for family and friends to gather, indulge in traditions, and celebrate this season of giving, it’s also hard to believe another year has passed.

In another “I can’t believe it’s already here” tradition, the new edition of the Children’s Hospital of Philadelphia Research Institute’s annual report is now available! The 2012 Research Annual Report details some of the many discoveries and accomplishments made at the Research Institute during fiscal year 2012. The report is available both as a PDF and as an interactive Web site.

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Dec 9 2012

Leukemia Patient Cancer-Free After Novel Treatment With Engineered Immune Cells

Emma relapses with acute lymphoblastic leukemia

Dr. Stephen Grupp's patient, Emma, relapses with acute lymphoblastic leukemia (ALL) in April 2011.

Cancer therapy for children has come a long way over the last several decades, and the cure rate for some forms of pediatric cancer is at an all-time high. Although this success rate offers tremendous hope and optimism, there are some children whose disease fails to respond to conventional treatment, leaving doctors to explore novel ways to conquer cancer.

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