Oct 9 2019

New Study Explores In-Home Sleep Apnea Evaluation for Children With Down Syndrome

By Barbara Drosey

Obstructive sleep apnea affects a disproportionate number of children with Down syndrome – 40 to 50 percent – compared to the 3 to 5 percent of their typically developing peers who are affected. Obstructive sleep apnea occurs more frequently during REM sleep, a sleep stage during which the body is completely relaxed, allowing the upper airways to become partially or completely blocked. Children with Down syndrome have midfacial hypoplasia, enlarged tongues, and baseline low muscle tone, all of which make them more prone to obstructive sleep apnea. These repeated obstructions in breathing can cause oxygen deprivation, carbon dioxide retention, and repeated awakenings that prevent children from getting a good night’s sleep.

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Oct 7 2019

Preventing Hemorrhage in Severely Injured Children

By Barbara Drosey

When a traumatic injury occurs, the countdown to an optimal chance at survival begins. With hemorrhage being the main cause of death within 24 hours postinjury, how bleeding is managed in those initial hours can greatly affect outcomes. It is within this critical window that Sage Myers, MD, MSCE, and her research team are trialing an intervention to prevent uncontrolled bleeding in children following traumatic injury.

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Oct 4 2019

In The News: Screening Tool for Autism, Recognition of ECMO Center Manager, Generous Gift for Palliative Care, Research Leadership Position, Non-verbal Children with Autism

By Nancy McCann

Take a look at who’s been making research headlines lately. This week we’re covering the accuracy of an autism spectrum disorder screening tool; the generous gift for palliative care, treatment, and research; and the international recognition of our Extracorporeal Membrane Oxygenation (ECMO) Center manager, James Connelly.

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Oct 2 2019

Off Campus: An EMT-on-Skis Comes to the Rescue

By Nancy McCann

Editor’s note: Welcome to our new blog series, “Off Campus.” Here you’ll discover what our amazing Research Institute employees do for fun, recreation, and the good of their communities once they leave the city behind. And if you know someone in your department or lab with a fascinating hobby or interest, we’d like to hear about it!

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Sep 30 2019

Balancing the Bench and the Bedside: Q&A With Jay Storm, MD

During Childhood Cancer Awareness Month and year-round, we love to see our patient families invested in our cancer research at Children’s Hospital of Philadelphia – whether it’s by attending events like the  Parkway Run & Walk or just sheer curiosity about the projects our scientists have in the works.

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Sep 27 2019

Don’t Go It Alone: The Successful Mentor-Mentee Relationship

Michael Marks, PhD, and Jing Karchin, PhD, were among three mentor-mentee pairs who participated in a panel discussion during the weeklong celebration of National Postdoc Appreciation Week.

By Barbara Drosey

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Sep 26 2019

Tour the Cores: Aquatic Zebrafish Core and its Underwater Superheroes

By Nancy McCann

Recent headlines have turned wee creatures called zebrafish into underwater superheroes: “The Boy Was Dying. Zebrafish Helped Save His Life,” and “CHOP Pulls off a Miraculous Treatment Thanks to Zebrafish, Dedicated and Brilliant Physicians and A Strong Young Boy.”

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Sep 20 2019

In the News: Pre-transplant Communication, Working Memory and Driving, Master Regulator Gene in Schizophrenia, Girls’ Concussion Care, Baby Brain Development

A slight chill on the air and the rustling of falling leaves means it’s time to grab your favorite pumpkin spice beverage and read our latest roundup of research news. Investigators from Children’s Hospital of Philadelphia’s Center for Injury Prevention and Research shared findings in concussion research and preventing car crashes among teens. Scientists in the Raymond G. Perelman Center for Cellular and Molecular Therapeutics discovered a gene that could help guide future treatment for schizophrenia, and a pilot grant from the Center for Pediatric Clinical Effectiveness will support aims to improve pre-transplant communication with patients and their families. As you savor the last few sips from your cup, learn about CHOP researchers’ contributions to a special journal issue on baby brain development. 

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Sep 19 2019

Where Are They Now? Former Postdocs Talk Life After CHOP

Life after leaving research training is an open road for postdoctoral fellows full of potential career opportunities. Some involve innovative research in academia and industry, and others include exciting new responsibilities in non-research positions. At Children’s Hospital of Philadelphia Research Institute, our postdocs go on to become teaching-focused faculty, consultants, principal investigators, journal editors, and in some cases, all of the above. 

To celebrate the 10th anniversary of National Postdoc Appreciation Week — and to guide current and future postdocs who might have a big question mark when it comes to their career paths — we connected with four former postdoctoral fellows who utilize the unique experience they gained at CHOP in a variety of different roles. Scroll down for some words of wisdom and inspiration from our postdoctoral alumni!

 

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Sep 17 2019

Off Campus: ‘Down East’ Fun for the Whole Family

By Nancy McCann

Editor’s note: Welcome to our new blog series, “Off Campus.” Here you’ll discover what our amazing Research Institute employees do for fun, recreation, and the good of their communities once they leave the city behind. And if you know someone in your department or lab with a fascinating hobby or interest, we’d like to hear about it!

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