Jul 18 2018

CHOP’s Inflammatory Bowel Disease Symposium Attracts Leading Experts

With the rate of inflammatory bowel disease (IBD) continuing to rise, especially in the hard-the-treat population of young children, the timing couldn’t be better for the Children’s Hospital of Philadelphia’s “Personalized IBD and VEO-IBD: Genomics, Microbiome, Biologics, and Beyond” symposium.

This symposium was of particular interest because of the unique combination of the latest research developments with the most up to date advances in clinical care for very-early-onset inflammatory bowel disease (VEO-IBD) and pediatric IBD, said course Co-director Judith R. Kelsen, MD, director of CHOP’s Very Early Onset Inflammatory Bowel Disease Clinic.

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Jul 16 2018

Team Huddles and Positive Feedback Enhance Research Participant Recruitment

Editor’s Note: Our guest blogger, Lindsay Waqar, MPH, CCRC, is the lead clinical research coordinator for the Division of Rheumatology at Children’s Hospital of Philadelphia. In this guest blog, she describes a collaborative quality improvement project presented at the Eighth Annual CHOP Quality and Safety Day between her research team and clinical fellows’ team to improve communication and research recruitment across the division.

What happens when researchers and clinicians team up to improve the identification of eligible research patients newly diagnosed with a chronic condition? Areas of change are discussed, low effort/high impact interventions are implemented, and research recruitment rates improve. This was the goal of the Division of Rheumatology’s fellow quality improvement project for FY18.

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Jul 13 2018

In the News: ALSF Epidemiology Grant, Button Battery Guidelines, PolicyLab Anniversary, EHR-Phenolyzer, Distracted Driving

In this week’s roundup of headlines at Children’s Hospital of Philadelphia, our research takes a leap into real-world applications. Learn how a study from ear, nose, and throat experts at CHOP helped to inform new button battery injury guidelines from the National Poison Center, why a software tool that mines through genomics data can improve genetic diagnoses, and what PolicyLab plans to achieve at their upcoming 10thanniversary forum, “Charting New Frontiers in Children’s Health Policy and Practice.” Don’t miss a chance to discover the latest in research news!

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Jul 10 2018

Do Oral Antibiotics Play a Role in Kidney Stone Prevalence Increase in Youth?

The Findings: Children and adults treated with five classes of oral antibiotics have a significantly higher risk of developing kidney stones. The five classes include oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins. Patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones. For broad-spectrum penicillins, the increased risk was 27 percent higher. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics. The risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

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Jul 6 2018

Eaise Family Rallies for Brain Tumor Research

Debbie Eaise remembers the day her 18-year-old son, Kevin, walked onto the University of Pennsylvania campus where he is set to play for the Penn Quakers baseball team this fall. From Meiklejohn Stadium, Penn’s home field, you can pitch a baseball and reach Children’s Hospital of Philadelphia, said Debbie — a proximity so palpable that she could see the change in her son’s face and sense his comfort level at ease while he toured his future school.

As her husband, Kevin Sr., and others have noted, Kevin has come full circle. It was right there on the Penn-CHOP campus, after all, with its skyline of medical buildings, that Kevin and his family’s life changed inextricably, ushering in what Debbie describes as their “new normal.”

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Jun 29 2018

In the News: Neuroscience of Driving, ASD Reward Circuitry, Orthopaedics Meeting, Diva De León-Crutchlow

Our latest roundup of research headlines from Children’s Hospital of Philadelphia is all about connecting the dots — whether it’s between two disciplines that come together in a common research mission, or discovering answers to previously unknown research questions. Read on to learn more about the Neuroscience of Driving Research Program, a collaboration between our Center of Injury Research and Prevention (CIRP) and the neuroradiology MEG (magnetoencephalography) Imaging Center at CHOP, along with novel findings that advance our understanding of how the brain processes rewards in individuals with autism spectrum disorder(ASD), and more.

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Jun 27 2018

Stephen P. Hunger, MD, Receives Prestigious George R. Buchanan Lectureship Award

Stephen P. Hunger, MD

Stephen P. Hunger, MD, has received numerous honors throughout his decorated career. However, winning the George R. Buchanan Lectureship Award from the American Society of Pediatric Hematology/Oncology (ASPHO) had particularly special meaning to the chief of the Division of Oncology and director of the Center for Childhood Cancer Research at Children’s Hospital of Philadelphia.

Recognized internationally in the field of pediatric leukemia clinical care and research, Dr. George R. Buchanan— past president of ASPHO and a renowned pediatric hematology physician-researcher — was very supportive of Dr. Hunger early in his career.

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Jun 25 2018

Getting in Step: Scientists Suggest Eosinophilic Esophagitis Part of Allergic March

New research findings by physician-scientists at Children’s Hospital of Philadelphia suggest that eosinophilic esophagitis (EoE) can be added as another “step” on the allergic march.

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Jun 22 2018

Supporting Our Scholars at First Postdoctoral Fellow Town Hall

“What does Children’s Hospital of Philadelphia do to support you as postdocs, and how can we do better?” That was the key question addressed at the first-ever Annual Postdoctoral Fellow Town Hall, hosted by the Office of Postdoctoral Affairs (OPA) at the Research Institute June 20.

Taking the form of a Q&A panel session, the event gathered postdoctoral scholars across diverse departments of the Research Institute along with administrative and faculty leaders who direct research support and training programs. The goal: Hear from our talented and hard-working fellows on how the Research Institute can help to propel them toward a future of breakthroughs.

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Jun 20 2018

Researchers Head to Botswana to Study Antibiotic Use in Hospitalized Children

Eimear Kitt, MBBCh BAO

The tide of antibiotic resistance continues to rise worldwide, and it is taking Eimear Kitt, MBBCh BAO (Hons), a third-year fellow in Infectious Diseases, and her study team to Botswana in sub-Saharan Africa this summer to prospectively collect information on antibiotic use in hospitalized children. When they return to Children’s Hospital of Philadelphia and analyze their data, their findings will help to inform strategies to improve antibiotic stewardship in low- and middle-income settings.

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