Tag Archive: Mitochondria

Sep 08 2017

CAR-T Cell Approval, Hope on Wheels, Task Force on Pregnant Women, Taking Flight for Autism, NFL Concussion Research, Doug Wallace

September marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research.

Permanent link to this article: http://blog.research.chop.edu/in-the-news-car-t-cell-approval-hope-wheels-task-force-pregnant-women-taking-flight-autism-nfl-concussion-research-doug-wallace/

Aug 23 2017

Mitochondrial Gene Defects Associated With Autism Traced Back to Ancient Times

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.

Permanent link to this article: http://blog.research.chop.edu/mitochondrial-gene-defects-associated-autism-traced-back-ancient-times/

Jan 12 2017

Novel Imaging Tool Estimates Energy Production in Mitochondrial Diseases

Fitness tools that monitor your daily use of energy, from counting steps to tracking sleep, have exploded in popularity. Researchers are developing better noninvasive, high-resolution methods to estimate how well the fundamental source of that energy — your mitochondria — are working, and they have recently had some important successes.

Permanent link to this article: http://blog.research.chop.edu/novel-imaging-tool-estimates-energy-production-mitochondrial-diseases/

Oct 21 2016

CHOP Research In the News: Cancer Moonshot Yields Data-Sharing Initiatives, Hemophilia Surprise, Mitochondrial Medal

Buckle your seatbelts because this has been a busy week for research news at Children’s Hospital of Philadelphia.

Permanent link to this article: http://blog.research.chop.edu/chop-research-news-cancer-moonshot-yields-data-sharing-initiatives-hemophilia-surprise-mitochondrial-medal/

May 24 2016

Underpinnings of Neuropsychiatric Disease: A Behavioral Health Research Q&A

A self-proclaimed “geeky student” in high school, Stewart Anderson, MD, a research psychiatrist, always dreamed of being a scientist. He wandered through various fields — anthropology, archeology, geology, astronomy – before becoming fascinated with learning about the brain.

Permanent link to this article: http://blog.research.chop.edu/underpinnings-neuropsychiatric-disease-behavioral-health-research-qa/

Dec 17 2015

Mitochondria Affect How We Respond to Stressful Environments

New research suggests that the tiny structures inside our cells that generate energy, called mitochondria, may play a role in our mind-body interactions and how we respond to stressful environments.

Permanent link to this article: http://blog.research.chop.edu/mitochondria-affect-how-we-respond-to-stressful-environments/

Nov 04 2015

Tiny Mitochondria Play Outsized Role in Human Evolution and Disease

Mitochondria are not only the power plants of our cells; these tiny structures also play a central role in our physiology. Furthermore, by enabling flexible physiological responses to new environments, mitochondria have helped humans and other mammals to adapt and evolve throughout the history of life on earth.

Permanent link to this article: http://blog.research.chop.edu/tiny-mitochondria-play-outsized-role-in-human-evolution-and-disease/

Sep 03 2015

Mitochondrial Disease and Diabetes Good Companions in Research

Certain defects in the way the mitochondria work may lead to diabetes, and the ways our bodies adapt to high blood sugars share many features with the ways our bodies respond to mitochondrial disease.

Permanent link to this article: http://blog.research.chop.edu/mitochondrial-disease-and-diabetes-good-companions-in-research/

Jul 06 2015

Experts Target Mitochondrial Dysfunction After Pediatric TBI

The World Health Organization predicts pediatric traumatic brain injury (TBI) will become a major cause of death and disability of children within the next several years.

Permanent link to this article: http://blog.research.chop.edu/experts-target-mitochondrial-dysfunction-after-pediatric-tbi/

Apr 21 2015

Restoring Cellular Energy Could Lead to Mitochondrial Disease Treatments

By using existing human drugs to improve metabolism and restore shortened lifespans in microscopic worms, scientists have set the stage for human clinical trials of possible innovative therapies for mitochondrial disease.

Permanent link to this article: http://blog.research.chop.edu/restoring-cellular-energy-could-lead-to-mitochondrial-disease-treatments/

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