Tag Archive: gene

Feb 09 2016

CHOP Research Annual Report 2015: The Future Is Here — Don’t Miss It

Scientific minds are imagining. Sophisticated machines are harnessing genetic data. An invisible universe of microbes is revealing new insights into disease. Discoveries are changing children’s worlds. Every second of every day is filled with wonder at The Children’s Hospital of Philadelphia Research Institute.

Permanent link to this article: http://blog.research.chop.edu/chop-research-annual-report-2015-the-future-is-here-dont-miss-it/

Nov 26 2014

International Team Finds Blood Disorder Mutation

An international team of gene experts has identified a mutation that causes aplastic anemia, a serious blood disorder in which the bone marrow fails to produce normal amounts of blood cells.

Permanent link to this article: http://blog.research.chop.edu/international-team-finds-blood-disorder-mutation/

Apr 02 2014

Prominent Gene Therapy Expert Joins CHOP

Beverly L. Davidson, PhD, a nationally prominent expert in gene therapy, joined The Children’s Hospital of Philadelphia on April 1.

Permanent link to this article: http://blog.research.chop.edu/prominent-gene-therapy-expert-joins-chop/

Feb 19 2014

Study Leads to Increased Heart Disease Risk Understanding

Most of us have heard of the “good cholesterol” and “bad cholesterol” coursing through our bloodstream. In the conventional wisdom of the past 30 years, having more of the “good” variety — high-density lipoprotein, or HDL — can lower your risk of heart disease, while more “bad” cholesterol — low-density lipoprotein, or LDL — increases your risk.

Permanent link to this article: http://blog.research.chop.edu/study-leads-increased-heart-disease-risk-understanding/

Jan 14 2014

Flipping a Gene Switch Reactivates Fetal Hemoglobin, May Reverse Sickle Cell Disease

Hematologists have long sought to reactivate fetal hemoglobin as a treatment for children and adults with sickle cell disease (SCD). Researchers at CHOP have manipulated key biological events in adult blood cells to produce a form of hemoglobin normally absent after the newborn period.

Permanent link to this article: http://blog.research.chop.edu/flipping-gene-switch-reactivates-fetal-hemoglobin-may-reverse-sickle-cell-disease/

Nov 21 2013

International Team Discovers Childhood Asthma Gene

An international team of researchers, including several investigators from The Children’s Hospital of Philadelphia’s Center for Applied Genomics, recently discovered a gene associated with a high risk of severe childhood asthma.

Permanent link to this article: http://blog.research.chop.edu/international-team-discovers-childhood-asthma-gene/