Category Archive: Children’s Hospital of Philadelphia

Aug 31 2017

A Moment to Remember: First-of-its-Kind Cancer Treatment Approved by FDA

It was a pivotal moment that has turned into a new era for cancer immunotherapy. On April 17, 2012, Children’s Hospital of Philadelphia researchers for the first time treated a pediatric patient with a cellular therapy that used her own reprogrammed immune cells, called T cells, to attack her aggressive form of blood cancer.

Permanent link to this article: http://blog.research.chop.edu/moment-remember-first-kind-cancer-treatment-approved-fda/

Aug 29 2017

CHOP Scientists Advance Hemophilia Research With Bayer Awards

While hemophilia is a lifelong condition, breakthroughs in the laboratory are driving novel treatments, and thanks to recently announced grants from the Bayer Hemophilia Awards Program (BHAP), scientists at Children’s Hospital of Philadelphia will be able to continue conducting even more investigations.

Permanent link to this article: http://blog.research.chop.edu/chop-scientists-advance-hemophilia-research-bayer-awards/

Aug 04 2017

Got Skills? What it Takes to be a Learning Health System Researcher

Don’t let those crisp, white lab coats fool you. While researchers share the ultimate goal of reaching new findings that can advance the best possible medical care, they aren’t all the same.

Permanent link to this article: http://blog.research.chop.edu/got-skills-takes-learning-health-system-researcher/

Aug 01 2017

Can Electronic Alerts Help Identify Sepsis in Sick Children?

A two-step electronic alert system successfully reduced missed sepsis diagnoses in children by 76 percent. The new pediatric protocol, which incorporates the use of vital signs, risk factors, and a clinician’s judgment, shows promise as a sensitive and specific tool that can help pediatricians working in the emergency department (ED) save lives.

Permanent link to this article: http://blog.research.chop.edu/snapshot-science-can-electronic-alerts-help-identify-sepsis-sick-children/

Jul 18 2017

Do Researchers Need Standardized Dosing for Infant Anticancer Drug Trials?

Researchers from the Children’s Oncology Group (COG) have developed a new standardized dosing method for anticancer drugs in infants to use across all COG clinical trials. This unified method, based on dose banding and organized into tables for different drugs and dose levels, will address the limitations and variability that researchers can encounter in current methods.

Permanent link to this article: http://blog.research.chop.edu/researchers-need-standardized-dosing-infant-anticancer-drug-trials/

Jul 11 2017

How Peacekeeper Cells Prevent Autoimmune Disease: Q&A with The Oliver Lab

In the lab of Paula Oliver, PhD, associate professor of Pathology at Children’s Hospital of Philadelphia, a group of researchers led by Awo Layman, PhD; Guoping Deng, PhD; and Claire O’Leary, PhD, studied the influential events that transpire when, as Dr. Layman described it to us, a type of immune cell called a regulatory T cell suffers a “loss of identity.”

Permanent link to this article: http://blog.research.chop.edu/peacekeeper-cells-prevent-autoimmune-disease-qa-oliver-lab/

Jun 28 2017

U.S. News National Survey Ranks CHOP Specialty Areas in Top Ten

Three cheers for our Children’s Hospital of Philadelphia team for once again achieving outstanding rankings in the U.S. News & World Report 11th annual Best Children’s Hospitals rankings. CHOP earned second place on the Honor Roll, a distinction awarded to pediatric centers that deliver exceptionally high-quality care across multiple specialties.

Permanent link to this article: http://blog.research.chop.edu/u-s-news-national-survey-ranks-chop-specialty-areas-top-ten/

Jun 13 2017

Do Assault-injured Youth Want Mental Health Care?

The majority of adolescent males receiving care in the pediatric emergency department after experiencing a violence-related injury — typically from peer assaults — felt they needed mental health services, according to a study by researchers from the Violence Intervention Program (VIP) at Children’s Hospital of Philadelphia.

Permanent link to this article: http://blog.research.chop.edu/snapshot-science-assault-injured-youth-want-mental-health-care/

Jun 09 2017

Could a Single Brain Scan Predict Autism Among High-risk Infants?

A neuroimaging scan at age 6 months may accurately predict autism spectrum disorder (ASD) among high-risk infants. The infants were considered to be at high risk because they had older siblings with ASD. Overall, the study team found 974 functional connections in the 6-month-olds’ brains that were associated with autism-related behaviors.

Permanent link to this article: http://blog.research.chop.edu/snapshot-science-single-brain-scan-predict-autism-among-high-risk-infants/

May 23 2017

Do the Effects of Neonatal Caffeine Therapy Persist in Middle School?

Caffeine therapy can help premature babies breathe stronger and sooner on their own. When a group of caffeine-treated premature babies reached middle school, the therapy appeared to reduce their risk of motor impairment – building on earlier follow-ups that show the treatment’s safety, efficacy, and developmental benefits for the babies at one-and-a-half years old.

Permanent link to this article: http://blog.research.chop.edu/snapshot-science-effects-neonatal-caffeine-therapy-persist-middle-school/

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