Category Archive: Mitochondrial-Genetic Disease Clinic

Apr 21 2015

Restoring Cellular Energy Could Lead to Mitochondrial Disease Treatments

By using existing human drugs to improve metabolism and restore shortened lifespans in microscopic worms, scientists have set the stage for human clinical trials of possible innovative therapies for mitochondrial disease.

Permanent link to this article: http://blog.research.chop.edu/restoring-cellular-energy-could-lead-to-mitochondrial-disease-treatments/

Feb 02 2015

Research Collaborative Aims to Advance Understanding of Preterm Birth

Researchers and physicians at The Children’s Hospital of Philadelphia are part of a transdisciplinary team that will apply sophisticated technology and methodology in molecular biology and genomics to help better understand the basis for preterm birth.

Permanent link to this article: http://blog.research.chop.edu/research-collaborative-aims-advance-understanding-preterm-birth/

Jul 30 2013

Mitochondrial Disease Signaling Network Discovered

Children’s Hospital researchers recently identified a network of signaling molecules that acts like a “fuse box,” regulating the effects of defective energy flow in mitochondrial respiratory chain diseases.

Permanent link to this article: http://blog.research.chop.edu/mitochondrial-disease-signaling-network-discovered/

Feb 14 2013

Unlocking the Secrets of Mitochondria

A team led by CHOP’s Marni J. Falk, MD, has expanded next-generation gene tools designed to sequence nuclear DNA to analyze a separate source of DNA — that found within mitochondria. Mitochondria are key suppliers of the energy needed for the multiple functions of our cells. Mitochondria contain their own DNA, and play a pivotal role in human health and disease.

Permanent link to this article: http://blog.research.chop.edu/unlocking-the-secrets-of-mitochondria/