Sep 22 2017

AAP Conference, PCORI Sickle Cell Research, Eagles Autism Challenge, Anxiety and Autism, New Immunotherapy Target for Neuroblastoma

CHOP Research In the NewsNotable awards, new autism initiatives, and a novel approach to managing sickle cell disease are all part of this week’s roundup of research news. As Children’s Hospital of Philadelphia experts made waves at the American Academy of Pediatrics (AAP) National Conference in Chicago, our local Philadelphia Eagles launched a new commitment to support autism research at CHOP and neighboring institutions back home. Read on to learn more about the latest headlines in CHOP research – including the detection of a potential immunotherapy target for neuroblastoma.

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-aap-conference-pcori-sickle-cell-research-eagles-autism-challenge-anxiety-autism-new-immunotherapy-target-neuroblastoma/

Sep 19 2017

Are Teens Still Building Bone After Attaining Their Adult Height?

The Finding:

Bone mineral accrual doesn’t keep pace with height growth prior to adolescence, according to a national study. After a teenager reaches adult height, bone mineral accrual tends to play catch-up: Roughly 10 percent of bone mass continues to accumulate after height growth is complete. The study findings also suggest that bone growth is site-specific, with bone mineral density developing at different rates in different parts of the skeleton.

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Permanent link to this article: http://blog.research.chop.edu/snapshot-science-teens-still-building-bone-attaining-adult-height/

Permanent link to this article: http://blog.research.chop.edu/research-heroes-neonatal-research-future-families-research-hero-clay-maresca-gives-back/

Sep 12 2017

Driving Evidence-Based Neonatology Forward: A Q&A With Barbara Schmidt, MD

As a student at McMaster University in Canada, Barbara Schmidt, MD, attending neonatologist at Children’s Hospital of Philadelphia, and director of Clinical Research, Neonatology at Penn Medicine, met William A. Silverman, MD, for the first time. Known as the father of neonatal intensive care, Dr. Silverman had given a talk that inspired Dr. Schmidt in its rigorous and questioning approach to newborn research and care: Both Dr. Silverman and Dr. Schmidt believed that nothing but the sharpest evidence should back the decisions we make when treating sick infants. Though she didn’t know it at the time, decades later, Dr. Schmidt would give a lecture on the same subject – one that, in fact, was in Dr. Silverman’s honor.

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Permanent link to this article: http://blog.research.chop.edu/driving-evidence-based-neonatology-forward-qa-barbara-schmidt-md/

Sep 08 2017

CAR-T Cell Approval, Hope on Wheels, Task Force on Pregnant Women, Taking Flight for Autism, NFL Concussion Research, Doug Wallace

CHOP Research In the NewsSeptember marks National Childhood Cancer Awareness Month, and this year at Children’s Hospital of Philadelphia, we kick-started the commemorative period on the heels of exciting news about breakthroughs in pediatric cancer immunotherapy research. Oncology investigators at CHOP also got a big boost in research funding from Hyundai’s nonprofit organization, Hope on Wheels. And that’s only the beginning: Since September marks the return of the football season, we’re thrilled to share the latest headlines on how the National Football League (NFL) is helping to drive concussion research.

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-car-t-cell-approval-hope-wheels-task-force-pregnant-women-taking-flight-autism-nfl-concussion-research-doug-wallace/

Sep 06 2017

CPCE Putting Research Into Practice With Pilot Grant Program

As summer fades, it’s exciting to embrace a new season filled with vibrant opportunities. The Center for Pediatric Clinical Effectiveness at Children’s Hospital of Philadelphia is ushering in the fall with a call for applications to its Pilot Grant Program. The program aims to support CHOP investigators who are interested in conducting studies designed to gather evidence about novel strategies that could shift current research or a clinical practice paradigm.

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Permanent link to this article: http://blog.research.chop.edu/cpce-putting-research-practice-pilot-grant-program/

Sep 05 2017

What Leads to Challenging Behaviors in Children with Autism?

snapshot science

The Findings:

A tantrum, a kick, a meltdown: In school-age children with autism, these aggressive and oppositional behaviors – described collectively as “challenging behaviors” – are some of the biggest struggles reported by parents and teachers. New research from the Center for Autism Research (CAR) at Children’s Hospital of Philadelphia suggests that these behaviors arise when children don’t have the skills they need to cope with situations or problems in an adaptive and healthy way. Working on skills such as emotion regulation, impulse control, cognitive inflexibility, and others that the researchers identified may be a helpful approach.

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Permanent link to this article: http://blog.research.chop.edu/snapshot-science-leads-challenging-behaviors-children-autism/

Aug 31 2017

A Moment to Remember: First-of-its-Kind Cancer Treatment Approved by FDA

It was a pivotal moment that has turned into a new era for cancer immunotherapy. On April 17, 2012, Children’s Hospital of Philadelphia researchers for the first time treated a pediatric patient with a cellular therapy that used her own reprogrammed immune cells, called T cells, to attack her aggressive form of blood cancer.

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Permanent link to this article: http://blog.research.chop.edu/moment-remember-first-kind-cancer-treatment-approved-fda/

Aug 29 2017

CHOP Scientists Advance Hemophilia Research With Bayer Awards

For children with hemophilia, every new research advance is a step toward a life filled with more activity, freedom, and adventure. The genetic condition, which affects roughly one in 5,000 births, causes children to bleed and bruise more easily than others – meaning that a simple cut, scrape, or small surgery can result in uncontrollable and excessive bleeding. While hemophilia is a lifelong condition, breakthroughs in the laboratory are driving novel treatments, and thanks to recently announced grants from the Bayer Hemophilia Awards Program (BHAP), scientists at Children’s Hospital of Philadelphia will be able to continue conducting even more investigations.

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Permanent link to this article: http://blog.research.chop.edu/chop-scientists-advance-hemophilia-research-bayer-awards/

Aug 25 2017

Kids First Data Center (DRC), CHOP’s Health Hero, Concussions on Air, Coping for Parents, Madeline Bell Modern Healthcare

CHOP Research In the NewsEvery day, we learn about the exciting new ways our investigators and staff at Children’s Hospital of Philadelphia modernize medicine and revolutionize healthcare for children. This week, we’re thrilled to report on a handful of new headlines about those breakthroughs, including a data-driven collaboration led by CHOP that aims to uncover the ties between cancer and birth defects through cloud-sharing technology, Madeline Bell’s recent inclusion into Modern Healthcare’s “100 Most Influential People in Healthcare” for 2017, and how our clinicians are improving community health beyond the clinic. Here are your latest highlights in CHOP research news.

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-kids-first-data-center-drc-chops-health-hero-concussions-air-coping-parents-madeline-bell-modern-healthcare/

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