May 03 2016

In Bench to Bedside: Finding Out Where It All Starts

Bench to BedsideThe latest issue of Bench to Bedside, our monthly newsmagazine, follows several researchers who are uncovering some of the earliest beginnings of disease processes.

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Permanent link to this article: http://blog.research.chop.edu/bench-bedside-finding-starts/

Apr 29 2016

CHOP Research In the News: Plastic Bronchitis, Baby BMI, Voice at the Vatican

CHOP Research In the NewsEvery week is full of discovery at The Children’s Hospital of Philadelphia. Among the highlights this week are a significant discovery and new treatment option in a heart surgery complication that affects young patients; a study of how to predict infants’ later obesity risk; and a CHOP cancer immunotherapy story hitting the world stage at an international conference.

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Permanent link to this article: http://blog.research.chop.edu/chop-research-news-plastic-bronchitis-baby-bmi-voice-vatican/

Apr 28 2016

Young Physician-Scientist Recognized for Pediatric Kidney Stone Research

Tasian_GregoryRGB-11_blogIt’s often surprising for parents to learn that their child has a kidney stone, a painful condition that is more common in adults but has dramatically increased in prevalence among pediatric patients over the last 25 years. Seeing this trend firsthand as a pediatric urologist and epidemiologist at The Children’s Hospital of Philadelphia, Gregory E. Tasian, MD, MSc, MSCE, realized that more research about pediatric kidney stone disease was desperately needed.

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Permanent link to this article: http://blog.research.chop.edu/young-physician-scientist-recognized-pediatric-kidney-stone-research/

Apr 26 2016

Hakon Hakonarson Honored for Excellence in Research Mentoring

Hakon HakonarsonThe Research Trainee Advisory Committee at The Children’s Hospital of Philadelphia Research Institute has named Hakon Hakonarson, MD, PhD, the inaugural winner of its Award for Excellence in Mentoring Research Trainees. The award recognizes faculty who effectively guide and monitor advanced training and professional development of research trainees at CHOP in an ongoing partnership sustained by mutual respect.

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Permanent link to this article: http://blog.research.chop.edu/hakon-hakonarson-honored-excellence-research-mentoring/

Apr 22 2016

CHOP Research In the News: Youth Violence, Novice Drivers, Obesity and Sexual Behavior

CHOP Research In the NewsThis week’s In the News tackles some risky business, from youth violence, to novice drivers, and the relationship between obesity in adolescence and sexual behavior. Read on to find out how researchers are exploring new approaches to these complex issues.

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Permanent link to this article: http://blog.research.chop.edu/chop-research-news-youth-violence-novice-drivers-obesity-sexual-behavior/

Apr 21 2016

Putting the Brakes on Allergic Response

allergic responseWhen you have a chronic allergic disorder, it’s easy to blame the trigger — an early pollen season or furry pet — but the real culprit is your own immune system. Designed to attack foreign substances such as bacteria and viruses, T cells are the immune system’s watchdog to recognize serious threats. But sometimes T cells can be too zealous and set in motion a signaling cascade that can cause allergic reactions to everyday things and even attack your body’s healthy cells by mistake.

“Inappropriate activation of immune cells is common in autoimmunity and also in allergic disease,” said Claire O’Leary, PhD, a postdoctoral fellow at The Children’s Hospital of Philadelphia. “Your immune system needs to learn to tolerate non-pathogenic immune insults while recognizing pathogenic organisms that it should mount a strong defense against.”

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Apr 19 2016

Coordinating Research with 80 Million Participants: A PCORnet Q&A

PCORnetNo question, discovering new treatments and cures for diseases is a critical task for medical research. But many patients and families stand to benefit just as much or more from understanding which existing therapies work best for whom.

Christopher Forrest, MD, PhD, a professor of Pediatrics at The Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, recently took on a new and influential position to help shape such comparative-effectiveness research at the national level. As newly appointed chair of the research committee for the national patient-centered clinical research network called PCORnet, he is helping research studies take shape to include a participant population of up to 80 million Americans who are part of 33 large research networks.

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Permanent link to this article: http://blog.research.chop.edu/coordinating-research-with-80-million-participants-a-pcornet-qa/

Apr 15 2016

CHOP Research In the News: Genetic Superheroes, Excess Bone, and Secondhand Smoke

CHOP Research NewsWelcome back to another weekly roundup of research news from The Children’s Hospital of Philadelphia!

This week’s stories have elements that sound like fiction, but all are real, new scientific and medical findings: A condition that turns the body’s soft tissues into bone has new hope for a future treatment. Genetic superheroes walk among us, and they may not even know it. And pediatricians may have a tool to double their success in helping their patients’ parents quit smoking. Read on for the details.

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Permanent link to this article: http://blog.research.chop.edu/chop-research-in-the-news-genetic-superheroes-excess-bone-and-secondhand-smoke/

Apr 12 2016

Growing Into Healthy Relationships: A Teen Dating Violence Q&A

teen dating violenceNo teenager wants to trade the sweaty palms and fluttering heartbeats that come with a first date or romantic relationship for real dread, fear, or even injury from dating violence. But it is a sad fact that emotional abuse, physical violence, and sexual violence do occur among some teen dating couples.

One in three teens in the U.S. report being a victim of physical, sexual, emotional or verbal abuse from a dating partner in the past 12 months, according to the National Council on Crime and Delinquency. Research into teen dating violence is helping to explain why it occurs and opening doors to intervene so that adolescents can develop healthy relationship skills they can sustain for life.

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Apr 08 2016

CHOP Research In The News: New Syndrome Named, National Honor for Pediatric Oncologist

CHOP Research In the NewsCheck out the most exciting research news from The Children’s Hospital of Philadelphia this week. From leading a group of international researchers who identified a new syndrome to working on a prestigious panel that will give guidance about ways to advance treatments for children with cancer, CHOP researchers are putting pediatric research in motion.

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