Jun 21 2017

Dr. Douglas Wallace Honored for Passion, Creativity in Biomedical Research

Doug WallaceEnergy continues to build for the role of the mitochondrion in health and disease, a field pioneered by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia. This week Dr. Wallace was named the recipient of the Dr. Paul Janssen Award for Biomedical Research, a high-profile achievement in recognition of Dr. Wallace’s scientific contributions as the founder of mitochondrial medicine.

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Permanent link to this article: http://blog.research.chop.edu/dr-douglas-wallace-honored-passion-creativity-biomedical-research/

Jun 16 2017

Alex’s Lemonade Kickoff, Baby Sleep Study, Military Families, Driving with ADHD, Reducing ED Pain

CHOP Research In the NewsRounding out a week of soaring temperatures and some exciting research at Children’s Hospital of Philadelphia, we bring you this week’s headline highlights, including last Friday’s fun-filled Alex’s Lemonade Stand Foundation kickoff event, a series of CHOP experts featured in mainstream media articles, breakthroughs in helping to reduce children’s pain in the emergency department, and more.

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-alexs-lemonade-kickoff-baby-sleep-study-military-families-driving-adhd-reducing-ed-pain/

Jun 13 2017

Do Assault-injured Youth Want Mental Health Care?

snapshot science

The Finding:

The majority of adolescent males receiving care in the pediatric emergency department after experiencing a violence-related injury — typically from peer assaults — felt they needed mental health services, according to a study by researchers from the Violence Intervention Program (VIP) at Children’s Hospital of Philadelphia. Eighty-nine percent of the study participants, who voluntarily enrolled in VIP following treatment in CHOP’s Emergency Department, said they wanted mental health therapy or suicide counseling. Fifty-six percent also identified the need for psychosocial support such as peer group sessions with other injured youth. These results suggest that clinical staff treating assault-injured youth should routinely inquire about mental health during healthcare conversations.

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Permanent link to this article: http://blog.research.chop.edu/snapshot-science-assault-injured-youth-want-mental-health-care/

Jun 09 2017

Could a Single Brain Scan Predict Autism Among High-risk Infants?

The Finding:

A neuroimaging scan at age 6 months may accurately predict autism spectrum disorder (ASD) among high-risk infants. The infants were considered to be at high risk because they had older siblings with ASD. Overall, the study team found 974 functional connections in the 6-month-olds’ brains that were associated with autism-related behaviors. A computer analysis of these neural signals’ patterns allowed researchers to identify with more than 96 percent accuracy which children would go on to be diagnosed with autism by 2 years of age, and which children would not.

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Permanent link to this article: http://blog.research.chop.edu/snapshot-science-single-brain-scan-predict-autism-among-high-risk-infants/

Jun 08 2017

Tuning in to Violence Prevention Initiative and Youth’s Voice in Research

The Violence Prevention Initiative (VPI) at Children’s Hospital of Philadelphia is a standout example of how our research is taking hold in communities, and now the entire country knows more about it after a live broadcast by “Good Morning America” at our Karabots Pediatric Care Center featuring an interview with Madeline Bell, president and chief executive officer of CHOP.

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Permanent link to this article: http://blog.research.chop.edu/tuning-violence-prevention-initiative-youths-voice-research/

Jun 06 2017

Meet the CHOP Mentors Changing Research Trainees’ Lives

CHOP MentorsOur research trainees at Children’s Hospital of Philadelphia go on to treat, teach, and investigate at some of the best medical institutions in the world. As the next generation of pediatric scientists, the mentors they meet while at CHOP don’t just influence their careers, but the future of children’s health, too. The Research Trainee Advisory Committee named this year’s Award for Excellence in Mentoring Research Trainee winners as Daniel Licht, MD,  pediatric neurologist; Matthew Weitzman, PhD, associate professor of Pathology; and Joanne Wood, MD, attending physician and research director of Safe Space: the Center for Child Protection and Health at CHOP.

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Permanent link to this article: http://blog.research.chop.edu/meet-chop-mentors-changing-research-trainees-lives/

Jun 02 2017

Good Morning America, Roberts Center Grand Opening, Center for Thoracic Insufficiency Reunion, Healthcare Innovator Award, Dragon Master Foundation

CHOP Research In the NewsOnwards and upwards: Last week’s grand opening of the new Roberts Center for Pediatric Research coincided with a series of exciting news that suggest breakthroughs are on the horizon, and also give us a sense of how far research at Children’s Hospital of Philadelphia has come. From a nationwide reunion of our Center for Thoracic Insufficiency patients to new leaps in digital healthcare innovation, these headlines thrill us just as much as the Roberts Center’s panoramic view of Philadelphia’s Schuylkill River. First on the docket: A spot on “Good Morning America”!

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-good-morning-america-roberts-center-grand-opening-center-thoracic-insufficiency-reunion-healthcare-innovator-award-dragon-master-foundation/

May 30 2017

Protecting Breastfed Babies in the First Days of Life: Q&A with Rebecca Ahrens-Nicklas, MD

breastfed babiesMore mothers are breastfeeding than ever before. However, getting breastfeeding going can be difficult. Babies with inherited metabolic disorders, such as medium-chain acyl-CoA dehydrogenase deficiency (let’s just call it MCAD) can be especially vulnerable to low blood sugar if they aren’t getting enough milk in the early days of breastfeeding. And while neonatologists and metabolic physicians have already gotten the hang of how to treat diagnosed MCAD, surprising new research shows a certain subset of newborns get ill before their MCAD screening results can even return to the doctor’s hands. Read the rest of this entry »

Permanent link to this article: http://blog.research.chop.edu/protecting-breastfed-babies-first-days-life-qa-rebecca-ahrens-nicklas-md/

May 23 2017

Do the Effects of Neonatal Caffeine Therapy Persist in Middle School?

snapshot science

The Finding:

Caffeine therapy can help premature babies breathe stronger and sooner on their own. When a group of caffeine-treated premature babies reached middle school, the therapy appeared to reduce their risk of motor impairment – building on earlier follow-ups that show the treatment’s safety, efficacy, and developmental benefits for the babies at one-and-a-half years old.

Why it matters:

About half of all premature babies will have apnea of prematurity, in which they experience difficulty breathing, hypoxic episodes (repetitive drops in their blood oxygen levels), and a higher risk for developing long-term disabilities like cerebral palsy. Previous follow-ups to this trial show that caffeine therapy helps to reduce the rate of these conditions when the babies reach 18 months. For parents, the important question remains: Do the treatment’s long-term benefits outweigh its long-term risks? According to this most recent follow-up, there seem to be no adverse effects.

Who conducted the study:

The Caffeine for Apnea of Prematurity (CAP) Trial Group involves an international array of investigators from Canada, Australia, and the UK, and its lead author is Barbara Schmidt, MD, an attending neonatologist at Children’s Hospital of Philadelphia.

How they did it:

More than 11 years ago, the researchers began to randomly assign 2,000 premature babies (who all weighed just 1 to 3 pounds) to either caffeine therapy at a dose equivalent to six cups of coffee, or placebo. The researchers followed these children’s academic performance, motor skills, and behavior over the years to find out how the caffeine therapy affected their mental and physical development.

Quick thoughts:

“The totality of our findings over the past decade reassures us that neonatal caffeine therapy is effective and safe when used as it was in the Caffeine for Apnea of Prematurity trial,” Dr. Schmidt said.

What’s next:

“Future research is required to evaluate whether longer therapy beyond the first discharge home from the neonatal unit is beneficial,” according to Dr. Schmidt. “A second question would be the examination of higher doses of caffeine.”

Where the study was published:

JAMA Pediatrics

Who helped fund the study:

The Canadian Institutes of Health Research supported the study.

Where to learn more:

You can read the study online at JAMA Pediatrics’ website and learn more about Dr. Schmidt’s research in pre-term babies on Cornerstone.

Permanent link to this article: http://blog.research.chop.edu/snapshot-science-effects-neonatal-caffeine-therapy-persist-middle-school/

May 19 2017

Sports Medicine Research Award, Concussion Research Collaboration, Stephan Grupp, PAS Meeting, Type 1.5 Diabetes

CHOP Research In the NewsOur latest research news roundup carries a hint of summer and exciting new beginnings: As more than 70 Children’s Hospital of Philadelphia experts traveled to sunny California for the annual Pediatric Academic Societies (PAS) Meeting, back at home, sports medicine research ramped up with new investigations into how we can protect kid’s health on (and off) the field. Keep reading for more of this week’s headlines, and learn how our researchers are staying active at the center line of pediatric research.

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Permanent link to this article: http://blog.research.chop.edu/in-the-news-sports-medicine-research-award-concussion-research-collaboration-stephen-grupp-pas-meeting-type-1-5-diabetes/

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